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The production of tumor necrosis factor-alpha by rat basophilic leukemia cells with triggering IgE receptor.

作者信息

Ohno I, Tanno Y, Yamauchi K, Ida S, Takishima T

机构信息

The First Department of Internal Meicine, Tohoku University School of Medicine, Sendai.

出版信息

Tohoku J Exp Med. 1988 Oct;156(2):209-10. doi: 10.1620/tjem.156.209.

DOI:10.1620/tjem.156.209
PMID:2976997
Abstract

We evaluated cytotoxic factor released from rat basophilic leukemia cells (RBL) sensitized with anti-ovalbumin (OVA) mouse serum after incubation with OVA. The cytotoxic activity of this factor was completely blocked by anti-mouse tumor necrosis factor-alpha (mTNF-alpha) specific antibody. Therefore, we concluded that by triggering the IgE receptor, RBL could produce and release TNF-alpha.

摘要

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The production of tumor necrosis factor-alpha by rat basophilic leukemia cells with triggering IgE receptor.
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引用本文的文献

1
Gene expression and production of tumour necrosis factor by a rat basophilic leukaemia cell line (RBL-2H3) with IgE receptor triggering.通过IgE受体触发的大鼠嗜碱性白血病细胞系（RBL - 2H3）的基因表达及肿瘤坏死因子的产生。
Immunology. 1990 May;70(1):88-93.
2
Production of tumour necrosis factor by mastocytoma P815 cells.肥大细胞瘤P815细胞产生肿瘤坏死因子。
Immunology. 1990 Feb;69(2):312-5.