Jacobs Jesse V, Henry Sharon M, Horak Fay B
Department of Rehabilitation and Movement Science, University of Vermont, Burlington, VT, United States.
Department of Rehabilitation Therapy, University of Vermont Medical Center, Burlington, VT, United States.
Front Neurol. 2018 May 2;9:313. doi: 10.3389/fneur.2018.00313. eCollection 2018.
Low back pain (LBP) has a point prevalence of nearly 10% and ranks highest in global disease burden for years lived with disability; Parkinson's disease (PD) ranks in the top 100 most disabling health conditions for years lost and years lived with disability (1). Recent evidence suggests that people with chronic, recurrent LBP exhibit many postural impairments reminiscent of a neurological postural disorder such as PD. We compare and contrast postural impairments associated with LBP and PD in order to inform treatment strategies for both conditions. The literature suggests that both LBP and PD associate with impaired proprioceptive function, sensory orientation during standing balance, anticipatory postural adjustments, automatic postural responses, and striatal-cortical function. Although postural impairments are similar in nature for LBP and PD, the postural impairments with LBP appear more specific to the trunk than for PD. Likewise, although both health conditions associate with altered striatal-cortical function, the nature of the altered neural structure or function differ for PD and LBP. Due to the high prevalence of LBP associated with PD, focused treatment of LBP in people with PD may render benefit to their postural impairments and disabilities. In addition, LBP would likely benefit from being considered more than just a musculoskeletal injury; as such, clinicians should consider including approaches that address impairments of postural motor control.
下背痛(LBP)的时点患病率近10%,在全球疾病负担中因残疾导致的寿命损失方面排名最高;帕金森病(PD)在因失能年数和残疾导致的寿命损失方面位列最致残的100种健康状况之中(1)。最近的证据表明,患有慢性复发性下背痛的人表现出许多姿势障碍,让人联想到诸如帕金森病之类的神经姿势障碍。我们比较并对比与下背痛和帕金森病相关的姿势障碍,以便为这两种疾病的治疗策略提供依据。文献表明,下背痛和帕金森病均与本体感觉功能受损、站立平衡时的感觉定向、预期姿势调整、自动姿势反应以及纹状体 - 皮质功能有关。尽管下背痛和帕金森病的姿势障碍在本质上相似,但下背痛的姿势障碍似乎比帕金森病更具躯干特异性。同样,尽管这两种健康状况均与纹状体 - 皮质功能改变有关,但帕金森病和下背痛的神经结构或功能改变的性质有所不同。由于与帕金森病相关的下背痛患病率很高,对帕金森病患者进行针对性的下背痛治疗可能会改善他们的姿势障碍和残疾状况。此外,下背痛可能不仅仅从被视为肌肉骨骼损伤中受益;因此,临床医生应考虑采用能够解决姿势运动控制障碍的方法。