Low Gary K K, Papapreponis Panayoti, Isa Ridzuan M, Gan Seng Chiew, Chee Hui Yee, Te Kian Keong, Hatta Nadia M
Department of Population Medicine, Faculty of Medicine and Health Sciences (FMHS), University Tunku Abdul Rahman (UTAR), Selangor.
Geospat Health. 2018 May 7;13(1):642. doi: 10.4081/gh.2018.642.
Increasing numbers of dengue infection worldwide have led to a rise in deaths due to complications caused by this disease. We present here a cross-sectional study of dengue patients who attended the Emergency and Trauma Department of Ampang Hospital, one of Malaysia's leading specialist hospitals. The objective was to search for potential clustering of severe dengue, in space and/or time, among the annual admissions with the secondary objective to describe the spatio-temporal pattern of all dengue cases admitted to this hospital. The dengue status of the patients was confirmed serologically with the geographic location of the patients determined by residency, but not more specific than the street level. A total of 1165 dengue patients were included in the analysis using SaTScan software. The mean age of these patients was 27.8 years, with a standard deviation of 14.2 years and an age range from 1 to 77 years, among whom 54 (4.6%) were cases of severe dengue. A cluster of general dengue cases was identified occurring from October to December in the study year of 2015 but the inclusion of severe dengue in that cluster was not statistically significant (P=0.862). The standardized incidence ratio was 1.51. General presence of dengue cases was, however, detected to be concentrated at the end of the year, which should be useful for hospital planning and management if this pattern holds.
全球登革热感染病例不断增加，导致该疾病引发的并发症造成的死亡人数上升。我们在此展示一项对登革热患者的横断面研究，这些患者来自马来西亚主要专科医院之一的安邦医院急诊科和创伤科。目的是在每年的入院病例中寻找严重登革热在空间和/或时间上的潜在聚集情况，次要目的是描述该医院收治的所有登革热病例的时空模式。患者的登革热状况通过血清学确诊，患者的地理位置由居住地确定，但不超过街道层面的具体信息。使用SaTScan软件对总共1165例登革热患者进行了分析。这些患者的平均年龄为27.8岁，标准差为14.2岁，年龄范围从1岁到77岁，其中54例（4.6%）为严重登革热病例。在2015年研究年度中，发现10月至12月出现了一组普通登革热病例群，但该群组中严重登革热病例的纳入在统计学上不显著（P = 0.862）。标准化发病率为1.51。然而，发现登革热病例普遍集中在年底，如果这种模式持续存在，这对于医院规划和管理将是有用的。
