Abbassi Imen Mariem, El Euch Mounira, Jaziri Fatima, Kefi Asma, Hamida Fethi Ben, Turki Sami, Abdelghani Khaoula Ben, Abdallah Taieb Ben
Department of Internal Medicine, University of Tunis El Manar, Tunis, Tunisia.
Research Laboratory of Kidney Diseases (LR00SP01), Charles Nicolle Hospital, Tunis, Tunisia.
Pan Afr Med J. 2022 Sep 6;43:9. doi: 10.11604/pamj.2022.43.9.21014. eCollection 2022.
Isolated laryngeal tuberculosis is rare and sometimes difficult to diagnose. It is the most common cause of laryngeal granuloma. We here report the case of a 58-year-old man, with no particular past medical history, hospitalized due to paroxysmal laryngeal dyspnea, dysphagia to solid foods and dysphonia evolving for 6 months without other associated signs. Laryngoscopic examination showed polyploid formation masking the glottic floor. Histological examination revealed epithelioid and gigantocellular granuloma, without caseous necrosis. Direct microscopic examination and culture were negative. The diagnosis of isolated laryngeal tuberculosis was made based on the endemicity in our country and the absence of other arguments in favor of another type of granulomatosis. Anti-tuberculosis therapy, combined with oral corticosteroids, was indicated based on the presence of severe upper airway edema and symptoms were resolved after 40 days of treatment.
孤立性喉结核较为罕见，有时难以诊断。它是喉肉芽肿最常见的病因。我们在此报告一例58岁男性病例，该患者无特殊既往病史，因阵发性喉喘鸣、固体食物吞咽困难及声音嘶哑6个月且无其他相关体征而住院。喉镜检查显示有掩盖声门底部的息肉样肿物形成。组织学检查显示上皮样和巨细胞肉芽肿，无干酪样坏死。直接显微镜检查和培养均为阴性。基于我国的地方流行情况以及无其他支持其他类型肉芽肿病的依据，诊断为孤立性喉结核。鉴于存在严重的上气道水肿，给予抗结核治疗并联合口服糖皮质激素，治疗40天后症状缓解。
