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眼前节光学相干断层扫描和超声生物显微镜在前节肿瘤成像中的应用

Anterior segment optical coherence tomography and ultrasound biomicroscopy in the imaging of anterior segment tumors.

作者信息

Pavlin Charles J, Vásquez Luz María, Lee Richard, Simpson E Rand, Ahmed Iqbal Ike K

机构信息

Department of Ocular Oncology, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada.

出版信息

Am J Ophthalmol. 2009 Feb;147(2):214-219.e2. doi: 10.1016/j.ajo.2008.08.023. Epub 2008 Oct 18.

DOI:10.1016/j.ajo.2008.08.023
PMID:18930449
Abstract

PURPOSE

To evaluate the utility of anterior segment optical coherence tomography (OCT) in the imaging of anterior segment tumors and compare the images to ultrasound biomicroscopy (UBM).

DESIGN

Prospective observational case series.

METHODS

Eighteen eyes of 18 patients with anterior segment tumors were evaluated at Princess Margaret Hospital. The evaluation included clinical examination, clinical photography, anterior segment OCT, and UBM. Comparison of images obtained by both methods was done.

RESULTS

Anterior segment OCT imaged small hypopigmented tumors with complete penetration. Cysts were incompletely imaged behind the iris pigment epithelium. Highly pigmented tumors, large tumors, and ciliary body tumors were incompletely penetrated. Even without complete penetration it was possible to differentiate cystic lesions from solid lesions. UBM penetrated all tumors completely.

CONCLUSIONS

Anterior segment OCT can penetrate small hypopigmented tumors and supply some information on internal characteristics of other tumors. UBM is preferable for clinical anterior tumor assessment and follow-up because of its superior ability to penetrate large tumors, highly pigmented tumors, and ciliary body tumors.

摘要

目的

评估眼前节光学相干断层扫描(OCT)在前节肿瘤成像中的应用,并将图像与超声生物显微镜(UBM)进行比较。

设计

前瞻性观察病例系列。

方法

在玛格丽特公主医院对18例患有前节肿瘤的患者的18只眼进行评估。评估包括临床检查、临床摄影、眼前节OCT和UBM。对两种方法获得的图像进行比较。

结果

眼前节OCT能对色素减退的小肿瘤进行完整穿透成像。囊肿在虹膜色素上皮后方成像不完全。色素沉着高的肿瘤、大肿瘤和睫状体肿瘤穿透不完全。即使没有完全穿透,也能够区分囊性病变和实性病变。UBM能完全穿透所有肿瘤。

结论

眼前节OCT可穿透色素减退的小肿瘤,并提供有关其他肿瘤内部特征的一些信息。由于UBM在穿透大肿瘤、色素沉着高的肿瘤和睫状体肿瘤方面具有更强的能力,因此在临床前节肿瘤评估和随访中更具优势。

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