School of Nursing, Fudan University, 305 Fenglin Road, Shanghai, 200032, China.
Nursing Department, Fudan University Cancer Hospital, 270 Dongan Road, Shanghai, 200000, China.
Support Care Cancer. 2018 Sep;26(9):2957-2971. doi: 10.1007/s00520-018-4257-3. Epub 2018 May 17.
To evaluate the existing body of evidence to determine the current state of knowledge regarding the perspectives of the following groups: (1) children with cancer, (2) family caregivers, and (3) healthcare professionals, about symptoms, as well as factors that may influence the symptom reports.
A systematic search was performed for all types of studies that included the perspectives of at least two groups of participants' symptom reports. Children included anyone younger than 19 years of age who was diagnosed with any type of cancer. Electronic searches were conducted in five English databases and four Chinese databases. The appraisal of methodological quality was conducted using the GRADE criteria. Data were extracted into matrix tables.
Thirty-three studies were included. The pediatric oncology symptoms reported by children, family caregivers, and healthcare professionals were synthesized. Findings suggested that family caregivers' symptom reports were more closely aligned with children's reports than with the healthcare professionals' reports. Influencing factors on the different symptom reports included the children's diagnosis, symptom characteristics, social-demographic factors, and family caregivers' psychosocial status.
Children with cancer should be the primary reporters for their symptoms. When there are reporters other than the children, the potential discrepancy between the different perspectives needs to be carefully considered.
评估现有证据，以确定以下群体对症状的看法现状：（1）癌症患儿；（2）照顾者；以及（3）医疗保健专业人员，以及可能影响症状报告的因素。
系统搜索了所有类型的研究，这些研究至少包括两个群体参与者的症状报告。患儿包括任何年龄在 19 岁以下被诊断患有任何类型癌症的人。在五个英文数据库和四个中文数据库中进行了电子检索。使用 GRADE 标准评估方法学质量。将数据提取到矩阵表中。
共纳入 33 项研究。综合了儿童、照顾者和医疗保健专业人员报告的儿科肿瘤症状。研究结果表明，照顾者的症状报告与儿童的报告更一致，而与医疗保健专业人员的报告不太一致。影响不同症状报告的因素包括儿童的诊断、症状特征、社会人口因素以及照顾者的心理社会状况。
癌症患儿应是其症状的主要报告者。当有除患儿以外的报告者时，需要仔细考虑不同视角之间的潜在差异。
