Nielsen Daiva E, El-Sohemy Ahmed
Department of Nutritional Sciences, University of Toronto, Room 350, 150 College St, Toronto, Ontario, M5S 3E2, Canada.
Per Med. 2012 Sep;9(7):739-749. doi: 10.2217/pme.12.79.
Personalized nutrition aims to prevent the onset and development of chronic diseases by targeting dietary recommendations to an individual's genetic profile. Gene-diet interactions that affect metabolic pathways relevant to disease risk are continuously being uncovered. Discoveries in the field of nutrigenomics demonstrate that some individuals may benefit from adhering to different dietary guidelines than others, depending on their genotype. Certain industries have already begun to capitalize on the anticipation that knowledge of genomic information could help prevent the risk of developing diseases. Although disclosure of genetic information has been associated with the adoption of positive health-related behaviors under certain circumstances, the effect of providing gene-based dietary advice on motivating adherence to favorable dietary changes is largely unknown.
个性化营养旨在通过根据个体的基因图谱制定饮食建议，预防慢性病的发生和发展。影响与疾病风险相关代谢途径的基因 - 饮食相互作用不断被发现。营养基因组学领域的研究发现表明，根据基因型不同，一些人可能比其他人更能从遵循不同的饮食指南中获益。某些行业已经开始利用人们的预期，即基因组信息知识有助于预防疾病发生风险。虽然在某些情况下，基因信息的披露与采取积极的健康相关行为有关，但提供基于基因的饮食建议对促使人们坚持有利的饮食改变的效果在很大程度上尚不清楚。
