Department of Neurology, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.
Center for Medical Statistics, Informatics and Intelligent Systems, Institute of Medical Information Management, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.
J Headache Pain. 2018 May 18;19(1):34. doi: 10.1186/s10194-018-0864-0.
To evaluate triptan use and overuse as well as prescription patterns in Austria based on a nationwide healthcare database because data on triptan use and overuse in Austria is missing.
We included all persons insured with one of 19 Austrian social security institutions in 2007. Inclusion criteria comprised an age of 18-99 years, known sex, and receipt of insurance benefits. We defined triptan use as ≥1 package of a triptan dispensed in 2007 and triptan overuse as ≥30 defined daily doses dispensed in at least one quarter.
Out of 8.295 million inhabitants in Austria, 7,426,412 persons (89.5%) were insured with a social insurance carrier and 5,918,487 persons of those insured (79.7%) fulfilled the inclusion criteria. Among the latter 33,062 persons (0,56%) were triptan users and 1970 (0.033%) were triptan overusers. The estimated proportion of persons with migraine using a triptan was less than 6%. Among users 5.9% were overusers of whom 55% overused triptans in ≥2 quarters of 2007. The median number of days of sick-leave was higher in triptan users than in non-users: due to any reason of sick-leave 12 vs. 10, p < 0.001, due to migraine 3 vs. 2, p < 0.001. The proportion of hospital admissions did not differ between triptan users and non-users.
The rate of triptan use is low in Austria but triptan users are at risk for triptan overuse. In triptan users more days of sick-leave and the same proportion of hospital admissions as in the older non-users suggest poorer health.
为了评估基于全国医疗保健数据库的奥地利曲坦的使用和滥用情况以及处方模式，因为奥地利缺乏关于曲坦使用和滥用的数据。
我们纳入了 2007 年参加 19 个奥地利社会保险机构之一的所有参保人员。纳入标准包括年龄 18-99 岁、已知性别和获得保险福利。我们将曲坦使用定义为 2007 年至少使用 1 个曲坦疗程包，曲坦滥用定义为至少一个季度开出 30 个以上规定日剂量。
在奥地利的 8295 万居民中，有 7426412 人（89.5%）参加了社会保险，其中 5918487 人（79.7%）符合纳入标准。在这些参保人中，有 33062 人（0.56%）是曲坦使用者，有 1970 人（0.033%）是曲坦滥用者。使用曲坦的偏头痛患者比例估计不足 6%。在使用者中，有 5.9%是滥用者，其中 55%在 2007 年至少两个季度滥用曲坦。曲坦使用者的病假天数中位数高于非使用者：因任何原因病假 12 天对 10 天，p<0.001，因偏头痛病假 3 天对 2 天，p<0.001。曲坦使用者和非使用者的住院比例没有差异。
奥地利的曲坦使用率较低，但曲坦使用者存在曲坦滥用风险。在曲坦使用者中，病假天数更多，与年龄较大的非使用者相比，住院比例相同，这表明他们的健康状况更差。
