Department of Pediatrics, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, 190011, India.
Department of Anesthesia and Critical Care, GMC, Srinagar, Jammu and Kashmir, India.
Indian J Pediatr. 2018 Nov;85(11):974-977. doi: 10.1007/s12098-018-2695-z. Epub 2018 May 19.
To study the prevalence of depression among caregivers of children with cystic fibrosis and its impact on the health and well being of these children.
This cross-sectional study was conducted in a tertiary care hospital from September 2015 through August 2016. Forty one parents of children receiving treatment at the Cystic fibrosis (CF) clinic were approached to be part of the study. Six families declined the request resulting in 85% recruitment rate. The Centre for Epidemiological Studies Depression Scale (CES-D) was used to assess depression score among caregivers. The CES-D provides clinical cut-off scores of ≥16 that help in identifying persons at risk for depression. CES-D was completed by the parent closely associated with care of the affected child. Main outcome measure was to find the number of caregivers of patients who has score of ≥16 on CES-D scale, and its effect on growth and respiratory exacerbations of the affected child.
A total of 23 fathers and 12 mothers participated in the study. The mean age of male and female caregivers was 30.9 ± 5.4 and 27.8 ± 4.7 y respectively. Eighteen (51.4%) caregivers scored above the clinical cut-off on the CES-D in the index study with mean score of 22.0 ± 4.0. The mean CES-D score among non-depressive caregivers was 7.76 ± 4.2. Significant negative association was found between parental depression and child's health. Children with high parental CES-D score suffered significantly more respiratory exacerbations (3.83 ± 1.2 episodes) in last six months than parents with low CES-D score (2.18 ± 1.28 episodes) (p value = 0.00). Similarly, stunting was more commonly seen in patients with high caregiver CES-D score (15 vs. 7; P value = 0.01).
A very high prevalence of caregiver depression was found in cystic fibrosis, which negatively impacted care and well being of the affected patients. Depression was more common in families with poor economic and education level.
研究囊性纤维化患儿照顾者中抑郁的发生率及其对患儿健康和幸福的影响。
这是一项横断面研究，于 2015 年 9 月至 2016 年 8 月在一家三级保健医院进行。对在囊性纤维化（CF）诊所接受治疗的 41 名儿童的父母进行了调查，邀请他们参与研究。有 6 个家庭拒绝了请求，招募率为 85%。采用流行病学研究中心抑郁量表（CES-D）评估照顾者的抑郁评分。CES-D 提供了临床临界分数≥16，有助于识别有抑郁风险的人。CES-D 由与照顾受影响孩子密切相关的父母完成。主要观察指标是确定 CES-D 量表得分≥16 的患者照顾者人数，以及其对受影响孩子生长和呼吸恶化的影响。
共有 23 名父亲和 12 名母亲参加了这项研究。男性和女性照顾者的平均年龄分别为 30.9±5.4 和 27.8±4.7 岁。18 名（51.4%）照顾者在本次研究中 CES-D 得分超过临床临界值，平均得分为 22.0±4.0。非抑郁照顾者的 CES-D 平均得分为 7.76±4.2。父母抑郁与孩子健康之间存在显著负相关。CES-D 评分高的父母的孩子在过去 6 个月中经历的呼吸恶化（3.83±1.2 次）明显多于 CES-D 评分低的父母（2.18±1.28 次）（p 值=0.00）。同样，CES-D 评分高的照顾者的孩子中发育迟缓更为常见（15 比 7；P 值=0.01）。
囊性纤维化患儿照顾者中抑郁的发生率非常高，这对患儿的护理和幸福产生了负面影响。经济和教育水平较差的家庭中抑郁更为常见。
