Aurshina Afsha, Alsheekh Ahmad, Kibrik Pavel, Hingorani Anil, Marks Natalie, Ascher Enrico
Vascular Institute of New York, Brooklyn, NY.
Vascular Institute of New York, Brooklyn, NY.
Ann Vasc Surg. 2018 Oct;52:158-162. doi: 10.1016/j.avsg.2018.03.017. Epub 2018 May 17.
Endovenous thermal ablation in the form of radiofrequency ablation (RFA) or endovenous laser ablation (EVLA) has quickly ascended to a prime position in the treatment of venous insufficiency. Although there are good data examining the rates of thrombotic complications, there is a relative paucity of data examining the recanalization rates after endovenous thermal ablation (ETA).
Data analysis was performed for 1475 thermal ablations in 485 patients from 2012 to 2015 as a retrospective chart review. RFA was performed in 1027 patients and EVLA in 448 patients. The target veins included the great saphenous vein (GSV) (778), short saphenous vein (SSV) (401), accessory saphenous vein (ASV) (140), and perforator veins (PV) (156). Data were collected from follow-up visit within 1 week of procedure, every 3 months for the first year, and every 6 months thereafter. Recurrence was defined as >500 ms for the GSV, SSV, and ASV and as >350 ms for the PV. Data for recanalization were also correlated with age, gender, laterality, presenting symptoms, and treated targeted vein.
The average age of the study population was 64.7 years (SD ± 15.6) with 66% women and 326 bilateral veins. At 1-week follow-up, women (2.6%) had higher recanalization rate (P = 0.018). Failure rate of obliteration for GSV and SSV were 0.8% and 0.8%, respectively (P = 0.98). PV had the highest failure rate (16.6%), followed by ASV (2.9%) (P < 0.001). At mean follow-up after 13.5 ± 12 months, PV (41.2%) and ASV (14.85) had higher recanalization rate than GSV (7.7%) and SSV (8.5%) (P < 0.001). Excluding PVs, no difference with recurrence rates between RFA (10%) and EVLA (8.8%) was observed at 1-week and 1-year follow-ups (P = 0.54). Also, 56% of patients with recanalization were symptomatic. Among these 1475 procedures, redo for recurrent symptoms were performed in 76. At 1 week, there was no difference between nonrepeated (92.7%) and repeated procedures (89.5%) (P = 0.41). However, 1 year later, there was significant difference between obliteration rate in nonrepeated (86.9%) and repeated (76.3%) procedures (P = 0.014).
These data do suggest low overall rates of recanalization after thermal ablation of the GSV and SSV. However, at 1-year follow-up, accessory veins had almost twice the recurrence rate as compared with GSV and SSV, and PV had almost 5 times the recurrence rate. There was no significant difference between RFA and EVLA in recanalization rates. Redo procedures in recanalized veins after venous ablation are effective with a success rate at 76.5%.
射频消融(RFA)或静脉腔内激光消融(EVLA)形式的静脉内热消融已迅速上升至静脉功能不全治疗的首要位置。尽管有关于血栓形成并发症发生率的良好数据,但关于静脉内热消融(ETA)后再通率的数据相对较少。
对2012年至2015年485例患者的1475次热消融进行数据分析,作为一项回顾性图表审查。1027例患者接受了RFA,448例患者接受了EVLA。目标静脉包括大隐静脉(GSV)(778条)、小隐静脉(SSV)(401条)、副隐静脉(ASV)(140条)和穿支静脉(PV)(156条)。在术后1周内的随访、第一年每3个月以及此后每6个月收集数据。复发定义为GSV、SSV和ASV大于500毫秒,PV大于350毫秒。再通数据也与年龄、性别、侧别、表现症状和治疗的目标静脉相关。
研究人群的平均年龄为64.7岁(标准差±15.6),女性占66%,双侧静脉326条。在1周随访时,女性(2.6%)的再通率较高(P = 0.018)。GSV和SSV的闭塞失败率分别为0.8%和0.8%(P = 0.98)。PV的失败率最高(16.6%),其次是ASV(2.9%)(P < 0.001)。在平均13.5±12个月的随访中,PV(41.2%)和ASV(14.8%)的再通率高于GSV(7.7%)和SSV(8.5%)(P < 0.001)。排除PV后,在1周和1年随访时,RFA(10%)和EVLA(8.8%)的复发率没有差异(P = 0.54)。此外,56%的再通患者有症状。在这1475例手术中,76例因复发症状进行了再次手术。在1周时,未重复手术(92.7%)和重复手术(89.5%)之间没有差异(P = 0.41)。然而,1年后,未重复手术(86.9%)和重复手术(76.3%)的闭塞率有显著差异(P = 0.014)。
这些数据确实表明GSV和SSV热消融后的总体再通率较低。然而,在1年随访时,副静脉的复发率几乎是GSV和SSV的两倍,PV的复发率几乎是5倍。RFA和EVLA的再通率没有显著差异。静脉消融后再通静脉的再次手术有效,成功率为76.5%。