Kubat Emre, Ünal Celal Selçuk, Geldi Onur, Çetin Erdem, Keskin Aydin, Karapınar Kasım
MD. Attending Physician, Department of Cardiovascular Surgery, Karabük Training and Research Hospital, Karabük, Turkey.
MD. Assistant Professor, Department of Cardiovascular Surgery, Karabük Training and Research Hospital, Karabük, Turkey.
Sao Paulo Med J. 2020 Mar;138(2):98-105. doi: 10.1590/1516-3180.2019.0230.r1.06112019. Epub 2020 Jun 1.
Diagnosis and treatment of small saphenous vein (SSV) insufficiency is of utmost importance for relieving chronic venous insufficiency symptoms.
To investigate the efficacy and safety of five different treatment approaches among patients with SSV insufficiency.
Two-center retrospective clinical study, conducted at cardiovascular surgery clinics in a local training and research hospital and a state hospital.
A total of 282 extremities of 268 patients with SSV insufficiency alone who were treated for symptomatic varicose veins between January 2012 and January 2017 were included in the study. All extremities included in the study were divided into five groups as follows: high ligation + stripping; radiofrequency ablation (RFA); cyanoacrylate closure (CAC); and endovenous laser ablation (EVLA) at the wavelengths 980 nm and 1,470 nm.
Although the recurrence rate at six months was similar among the treatment groups, we found significant differences in recurrence rates at one year, with lower rates in the CAC, RFA and 1,470 nm EVLA groups, compared with the other treatments (P = 0.005). No sural neuritis was observed in the CAC group. The pigmentation rate was higher in the two EVLA groups (980 nm and 1,470 nm).
Our study results showed that although CAC, RFA and EVLA at 1,470 nm seemed to be effective methods for treating SSV insufficiency alone, CAC and RFA had better aesthetic results than EVLA at 1,470 nm. We consider that endovenous non-thermal techniques for treating SSV insufficiency may be preferable because of relatively low risk of nerve injury.
小隐静脉功能不全的诊断和治疗对于缓解慢性静脉功能不全症状至关重要。
探讨五种不同治疗方法对小隐静脉功能不全患者的疗效和安全性。
在当地一家培训和研究医院的心血管外科诊所和一家国立医院进行的两中心回顾性临床研究。
纳入2012年1月至2017年1月期间因症状性静脉曲张接受治疗的268例单纯小隐静脉功能不全患者的282条肢体。研究中纳入的所有肢体分为以下五组:高位结扎+剥脱术;射频消融(RFA);氰基丙烯酸酯闭合术(CAC);以及波长为980nm和1470nm的腔内激光消融术(EVLA)。
尽管各治疗组六个月时的复发率相似,但我们发现一年时的复发率存在显著差异,与其他治疗方法相比,CAC、RFA和1470nm EVLA组的复发率较低(P = 0.005)。CAC组未观察到腓肠神经病变。两个EVLA组(980nm和1470nm)的色素沉着率较高。
我们的研究结果表明,尽管CAC、RFA和1470nm的EVLA似乎是单独治疗小隐静脉功能不全的有效方法,但CAC和RFA在美学效果上优于1470nm的EVLA。我们认为,由于神经损伤风险相对较低,腔内非热技术治疗小隐静脉功能不全可能更可取。