丙型肝炎病毒诊断与圣杯。
Hepatitis C Virus Diagnosis and the Holy Grail.
机构信息
The Kirby Institute, UNSW Sydney, High Street, Sydney, New South Wales 2052, Australia.
Médecins Sans Frontières Access Campaign, Rue de Lausanne 78 P.O Box 1016, Geneva CH-1211, Switzerland.
出版信息
Infect Dis Clin North Am. 2018 Jun;32(2):425-445. doi: 10.1016/j.idc.2018.02.010.
The world has embraced the call for global elimination of hepatitis C virus by 2030. The unprecedented speed of therapeutic development and increased access to direct-acting antivirals has made elimination a possibility. We must screen hundreds of millions of people to diagnose and treat those currently infected. Global access to hepatitis C virus diagnostics will be a keystone to success. Key challenges must be overcome and systems optimized to ensure widespread access to existing diagnostics. Although promising technologies may soon transform the landscape, innovative strategies are needed to stimulate investment and accelerate the development of point-of-care hepatitis C virus diagnostics.
全球已响应号召，力争在 2030 年前实现丙型肝炎病毒的全球消除。前所未有的治疗药物研发速度和更多直接作用抗病毒药物的应用，使得这一目标成为可能。我们必须对数亿人进行筛查，以诊断和治疗目前已感染者。全球获得丙型肝炎病毒诊断检测服务将是成功的关键。必须克服关键挑战并优化系统，以确保广泛获得现有诊断检测服务。虽然有前景的技术可能很快会改变这一局面，但仍需要创新策略来刺激投资并加速即时检测丙型肝炎病毒诊断技术的发展。
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