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英国中世纪后奇切斯特一具骨骼中广泛的骨膜新生骨形成:一例可能的前列腺癌转移病例。

Extensive periosteal new bone formation in a skeleton from post-Medieval Chichester, England: A probable case of metastatic prostatic carcinoma.

作者信息

Rando Carolyn, Waldron Tony

机构信息

UCL Institute of Archaeology, London, UK.

UCL Institute of Archaeology, London, UK.

出版信息

Int J Paleopathol. 2018 Jun;21:121-127. doi: 10.1016/j.ijpp.2017.07.004. Epub 2017 Jul 29.

DOI:10.1016/j.ijpp.2017.07.004
PMID:29778409
Abstract

An elderly male skeleton from a site in Chichester, UK, was found with a widespread periosteal reaction, principally affecting the axial skeleton and the pelvis. Radiography showed the presence of sclerosing infiltrates, mainly involving the lumbar vertebrae and pelvis. The differential diagnosis is discussed, reaching the conclusion that hypertrophic osteo-arthopathy (HOA) is the only reasonable alternative condition likely to produce such a widespread periosteal reaction as found here. HOA does not produce secondary deposits in the skeleton, however, and we conclude that his is most likely a case of prostatic carcinoma.

摘要

在英国奇切斯特一处遗址发现的一具老年男性骨骼,存在广泛的骨膜反应,主要影响中轴骨骼和骨盆。放射检查显示有硬化性浸润,主要累及腰椎和骨盆。文中讨论了鉴别诊断,得出结论:肥大性骨关节病(HOA)是唯一可能产生如此广泛骨膜反应的合理替代病症。然而,HOA不会在骨骼中产生继发性沉积物,我们得出结论,这很可能是一例前列腺癌病例。

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