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并存的鳞状细胞癌和高级别神经内分泌癌,小细胞型:宫颈中一种罕见的碰撞瘤。

Coexisting squamous cell carcinoma and high-grade neuroendocrine carcinoma, small cell type: a rare collision in cervix.

作者信息

Kaushal Seema, Mathur Sandeep R, Kumar Sunesh

机构信息

Department of Pathology, All India Institute of Medical Sciences, New Delhi, India.

Department of Obstetrics and Gynaecology, All India Institute of Medical Sciences, New Delhi, India.

出版信息

BMJ Case Rep. 2018 May 18;2018:bcr-2017-223127. doi: 10.1136/bcr-2017-223127.

DOI:10.1136/bcr-2017-223127
PMID:29778998
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5965757/
Abstract

Collision tumours of the uterine cervix are extremely uncommon with exact incidence not known. Unlike squamous cell carcinoma (SCC) and adenocarcinoma that are known to coexist, small cell neuroendocrine carcinoma (SCNEC) is rarely documented with other histological types in the cervix. We report such rare case of a collision tumour in cervix displaying dual histological component of SCNEC and SCC in a 36-year-old woman. The case is being presented because of its rarity and represents a unique and hitherto seldom-reported combination of two malignant tumours with distinct and often contrasting epidemiology, histology and prognosis coexisting in the same patient.

摘要

子宫颈碰撞瘤极为罕见,确切发病率尚不清楚。与已知共存的鳞状细胞癌(SCC)和腺癌不同,宫颈小细胞神经内分泌癌(SCNEC)很少与其他组织学类型同时出现。我们报告了一例罕见的子宫颈碰撞瘤病例,该病例发生在一名36岁女性身上,显示出SCNEC和SCC的双重组织学成分。之所以展示该病例,是因其罕见,它代表了两种恶性肿瘤独特且迄今鲜有报道的组合,这两种肿瘤在同一患者中共存,其流行病学、组织学和预后明显不同且往往相反。

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Indian J Cancer. 2015 Oct-Dec;52(4):603-4. doi: 10.4103/0019-509X.178436.
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Natural history and outcome of neuroendocrine carcinoma of the cervix.子宫颈神经内分泌癌的自然病史及预后
Gynecol Oncol. 2016 May;141(2):247-254. doi: 10.1016/j.ygyno.2016.02.008. Epub 2016 Feb 9.
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Co-existing of adenoid cystic carcinoma and invasive squamous cell carcinoma of the uterine cervix: a report of 3 cases with immunohistochemical study and evaluation of human papillomavirus status.宫颈腺样囊性癌与浸润性鳞状细胞癌并存:3例报告及免疫组化研究与人乳头瘤病毒状态评估
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Small cell type neuroendocrine carcinoma colliding with squamous cell carcinoma at esophagus.食管小细胞型神经内分泌癌与鳞状细胞癌碰撞并存。
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