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气象条件和空气污染对 A 型和 B 型急性主动脉夹层发生的影响。

The effect of meteorological conditions and air pollution on the occurrence of type A and B acute aortic dissections.

机构信息

Department of Emergency, West China Hospital, Sichuan University, Number 37, Guoxue Alley, Chengdu, 610041, Sichuan, China.

出版信息

Int J Biometeorol. 2018 Sep;62(9):1607-1613. doi: 10.1007/s00484-018-1560-0. Epub 2018 May 19.

Abstract

To explore the association of weather conditions and air pollutants with incidence risk of acute aortic dissection (AAD), we included patients who consecutively admitted to the emergency units of our hospital for AAD between Dec. 1, 2013, and Apr. 30, 2017. Their medical records were reviewed. The meteorological data (daily precipitation, minimal and maximal temperatures, mean atmospheric pressure, relative humidity) and air pollutants values [air daily index (AQI), aerodynamic diameter of 2.5 mm or less (PM2.5), aerodynamic diameter of 10 mm or less (PM10), ozone, nitrogen dioxide (NO2), carbon monoxide (CO), sulfur dioxide (SO2), and ozone (O3_8h)] over the same period were provided by the Chengdu Meteorological Bureau. Finally, a total of 345 patients were admitted with AAD. The results showed that the incidence of AAD was higher in winter than in summer (p < 0.001). Statistical analysis highlighted lower the atmospheric temperature, higher the incidence of AAD (p < 0.001). A significant correlation was found between air pollutants and AAD onset. AQI, PM2.5, SO2, and NO2 were independent predictors of incidence of AAD (OR = 1.006, p = 0.007; OR = 1.020, p < 0.001; OR = 1.037, p < 0.001; and OR = 0.925, p < 0.001; respectively). While, PM10, CO, and O3_8H had a neutral effect on risk of AAD onset. In conclusions, cold atmospheric temperature and larger daily temperature change were correlated with a higher incidence of AAD. AQI, PM2.5, and SO2 played important roles in triggering acute aortic events.

摘要

为了探讨天气条件和空气污染物与急性主动脉夹层(AAD)发病风险的关系,我们纳入了 2013 年 12 月 1 日至 2017 年 4 月 30 日期间连续因 AAD 入住我院急诊部的患者。我们回顾了他们的病历。同期由成都气象局提供气象数据(日降水量、最小和最大温度、平均大气压、相对湿度)和空气污染物值(空气质量指数(AQI)、空气动力学直径 2.5 毫米或以下(PM2.5)、空气动力学直径 10 毫米或以下(PM10)、臭氧、二氧化氮(NO2)、一氧化碳(CO)、二氧化硫(SO2)和臭氧(O3_8h))。最终,共有 345 名患者因 AAD 入院。结果显示,AAD 的发病率冬季高于夏季(p<0.001)。统计分析强调,大气温度越低,AAD 的发病率越高(p<0.001)。空气污染物与 AAD 发病之间存在显著相关性。AQI、PM2.5、SO2 和 NO2 是 AAD 发病的独立预测因子(OR=1.006,p=0.007;OR=1.020,p<0.001;OR=1.037,p<0.001;OR=0.925,p<0.001;分别)。然而,PM10、CO 和 O3_8H 对 AAD 发病风险没有影响。总之,寒冷的大气温度和较大的日温差与 AAD 发病率升高相关。AQI、PM2.5 和 SO2 在引发急性主动脉事件中起重要作用。

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