Bán Ágnes, Németh Zsolt Ferenc, Szauter Adrienn, Soós Szilvia, Balaskó Márta
Fogorvos-tudományi Kar, Fogászati és Szájsebészeti Klinika, Pécsi Tudományegyetem Pécs.
Általános Orvostudományi Kar, Klinikai Központ, Transzlációs Medicina Intézet, Pécsi Tudományegyetem Pécs, Szigeti út 12., 7624.
Orv Hetil. 2018 May;159(21):831-836. doi: 10.1556/650.2018.31037.
Chronic parodontitis is a prevalent oral disease that may lead to the loss of teeth independently of caries. Some systemic diseases (e.g., diabetes mellitus, chronic renal failure) may aggravate chronic parodontitis. On the other hand, this oral disease may aggravate other systemic diseases. Earlier studies suggested a correlation between chronic parodontitis and very severe chronic obstructive pulmonary disease (COPD).
The aim of our study was the investigation of the correlation between chronic parodontitis and chronic obstructive pulmonary disease.
We have recruited patients of the Department of Dentistry, Oral and Maxillofacial Surgery, Medical School, University of Pécs, in the study. Volunteers were assigned into a COPD (n = 29) and control group (n = 45). Airflow limitation of the COPD group (FEV/FVC: 61.52 ± 3.2%) corresponded to GOLD 2 (global initiative for chronic obstructive lung disease; FEV: 52.66 ± 3.57%). Oral health assessment included mean and maximal clinical attachment loss, mobility of teeth, decayed/filled and missing teeth, Löe-Silness, oral hygiene and bleeding on probing indexes. One-way ANOVA and non-parametric Mann-Whitney tests were used for statistical analysis.
Oral health of the COPD group was worse than that of the controls. In this group the mean and maximal clinical attachment loss, mobility of teeth, the Löe-Silness, the oral hygiene and bleeding on probing indexes were higher.
Our results confirm the positive correlation between chronic parodontitis and a moderate level of chronic obstructive pulmonary disease. However, it is not clear whether the COPD-associated systemic inflammation aggravated the oral status or the chronic parodontitis influenced negatively chronic obstructive pulmonary disease. Orv Hetil. 2018; 159(21): 831-836.
慢性牙周炎是一种常见的口腔疾病，可独立于龋齿导致牙齿丧失。一些全身性疾病（如糖尿病、慢性肾衰竭）可能会加重慢性牙周炎。另一方面，这种口腔疾病也可能加重其他全身性疾病。早期研究表明慢性牙周炎与非常严重的慢性阻塞性肺疾病（COPD）之间存在关联。
我们研究的目的是调查慢性牙周炎与慢性阻塞性肺疾病之间的相关性。
我们招募了佩奇大学医学院牙科、口腔颌面外科的患者参与研究。志愿者被分为慢性阻塞性肺疾病组（n = 29）和对照组（n = 45）。慢性阻塞性肺疾病组的气流受限情况（FEV/FVC：61.52 ± 3.2%）符合慢性阻塞性肺疾病全球倡议（GOLD）2级（FEV：52.66 ± 3.57%）。口腔健康评估包括平均和最大临床附着丧失、牙齿松动度、龋/补/失牙情况、Löe-Silness指数、口腔卫生和探诊出血指数。采用单因素方差分析和非参数曼-惠特尼检验进行统计分析。
慢性阻塞性肺疾病组的口腔健康状况比对照组差。该组的平均和最大临床附着丧失、牙齿松动度、Löe-Silness指数、口腔卫生和探诊出血指数更高。
我们的结果证实了慢性牙周炎与中度慢性阻塞性肺疾病之间存在正相关。然而，尚不清楚与慢性阻塞性肺疾病相关的全身性炎症是否加重了口腔状况，或者慢性牙周炎是否对慢性阻塞性肺疾病产生了负面影响。《匈牙利医学周报》。2018年；159(21): 831 - 836。
