神经肌肉和胸壁疾病中的睡眠呼吸障碍。

Sleep-Disordered Breathing in Neuromuscular and Chest Wall Diseases.

机构信息

Department of Internal Medicine, Section of Pulmonary, Critical Care, and Sleep Medicine, Yale University, Yale University School of Medicine, 300 Cedar Street, PO Box 208057, New Haven, CT 06520-8057, USA.

出版信息

Clin Chest Med. 2018 Jun;39(2):309-324. doi: 10.1016/j.ccm.2018.01.009.

DOI:10.1016/j.ccm.2018.01.009

PMID:29779591

Abstract

Neuromuscular and chest wall diseases include a diverse group of conditions that share common risk factors for sleep-disordered breathing, including respiratory muscle weakness and/or thoracic restriction. Sleep-disordered breathing results from both the effects of normal sleep on ventilation and the additional challenges imposed by the underlying disorders. Patterns of sleep- disordered breathing vary with the specific diagnosis and stage of disease. Sleep hypoventilation precedes diurnal respiratory failure and may be difficult to recognize clinically because symptoms are nonspecific. Polysomnography has a role in both the diagnosis of sleep-disordered breathing and in the titration of effective noninvasive positive-pressure ventilation.

摘要

神经肌肉和胸壁疾病包括一组具有共同睡眠呼吸紊乱危险因素的疾病，包括呼吸肌无力和/或胸壁受限。睡眠呼吸紊乱是由正常睡眠对通气的影响以及潜在疾病带来的额外挑战所导致的。睡眠呼吸紊乱的模式因具体诊断和疾病阶段而异。睡眠低通气先于日间呼吸衰竭，并且由于症状不具有特异性，临床上可能难以识别。多导睡眠图在睡眠呼吸紊乱的诊断和有效无创正压通气滴定中都有作用。