Sagawa Junji, Yoshii Yoko, Kubota Mitsunobu
Department of Endocrinology and Diabetes, National Hospital Organization KURE Medical Center, Japan.
Intern Med. 2018 Oct 1;57(19):2859-2863. doi: 10.2169/internalmedicine.0878-18. Epub 2018 May 18.
The patient was a 32-year-old Japanese woman who was given a 75-g oral glucose tolerance test at the 35th week of pregnancy and was normoglycemic. She had excessive thirst and polyuria from 15 days after delivery. When she visited for the 1-month postpartum checkup, her plasma glucose level was 479 mg/dL, HbA1c was 7.4%, and urinary C-peptide was 1.1 μg/mL; she was therefore diagnosed with fulminant type 1 diabetes mellitus associated with pregnancy. All physicians should be aware of this disease so as to provide a prompt diagnosis and emergency treatment and consequently improve the maternal prognosis.
该患者为一名32岁的日本女性，在妊娠第35周时接受了75克口服葡萄糖耐量试验，结果显示血糖正常。产后15天起，她出现了口渴和多尿症状。在产后1个月进行检查时，她的血浆葡萄糖水平为479毫克/分升，糖化血红蛋白（HbA1c）为7.4%，尿C肽为1.1微克/毫升；因此，她被诊断为与妊娠相关的暴发性1型糖尿病。所有医生都应了解这种疾病，以便能够及时诊断并进行紧急治疗，从而改善产妇的预后。
