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产后15天出现的暴发性1型糖尿病:与产科医生合作进行诊断

Fulminant Type 1 Diabetes Mellitus Presenting 15 Days after Delivery Diagnosed in Cooperation with Obstetricians.

作者信息

Sagawa Junji, Yoshii Yoko, Kubota Mitsunobu

机构信息

Department of Endocrinology and Diabetes, National Hospital Organization KURE Medical Center, Japan.

出版信息

Intern Med. 2018 Oct 1;57(19):2859-2863. doi: 10.2169/internalmedicine.0878-18. Epub 2018 May 18.

Abstract

The patient was a 32-year-old Japanese woman who was given a 75-g oral glucose tolerance test at the 35th week of pregnancy and was normoglycemic. She had excessive thirst and polyuria from 15 days after delivery. When she visited for the 1-month postpartum checkup, her plasma glucose level was 479 mg/dL, HbA1c was 7.4%, and urinary C-peptide was 1.1 μg/mL; she was therefore diagnosed with fulminant type 1 diabetes mellitus associated with pregnancy. All physicians should be aware of this disease so as to provide a prompt diagnosis and emergency treatment and consequently improve the maternal prognosis.

摘要

该患者为一名32岁的日本女性,在妊娠第35周时接受了75克口服葡萄糖耐量试验,结果显示血糖正常。产后15天起,她出现了口渴和多尿症状。在产后1个月进行检查时,她的血浆葡萄糖水平为479毫克/分升,糖化血红蛋白(HbA1c)为7.4%,尿C肽为1.1微克/毫升;因此,她被诊断为与妊娠相关的暴发性1型糖尿病。所有医生都应了解这种疾病,以便能够及时诊断并进行紧急治疗,从而改善产妇的预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a879/6207811/2d160e34c2fe/1349-7235-57-2859-g001.jpg

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