Directorate General for Disease Surveillance and Control, Ministry of Health, Muscat, Oman; Al-Nahdha Hospital, Muscat, Oman.
Directorate General for Disease Surveillance and Control, Ministry of Health, Muscat, Oman.
Int J Infect Dis. 2018 Jun;71:94-99. doi: 10.1016/j.ijid.2018.04.795. Epub 2018 May 26.
To assess the impact of capacity-building interventions introduced by the Oman National AIDS Programme on the quality of HIV care in the country.
HIV viral load (VL) suppression and loss to follow-up (LTFU) rates were calculated for the period before (in December 2015; n=1098) and after (in June 2017; n=1185) the introduction of the interventions: training, support, and care pathway development. Three HIV VL cuts-offs at last measurement in the year of interest were used to define VL suppression.
In the intention-to-treat (ITT) analysis, rates of VL <200 copies/ml and <1000 copies/ml increased from 51.9% in 2015 to 65.5% in 2017 (relative risk (RR) 1.26, 95% confidence interval (CI) 1.17-1.36) and from 58.1% in 2015 to 70.9% in 2017 (RR 1.22, 95% CI 1.14-1.30), respectively; p<0.0001 for both. Similarly, in the on-treatment analysis, rates of VL <200 copies/ml and <1000copies/ml increased from 64.2% in 2015 to 76.9% in 2017 (RR 1.20, 95% CI 1.12-1.28) and from 71.9% in 2015 to 83.2% in 2017 (RR 1.16, 95% CI 1.10-1.22), respectively. Fewer patients were LTFU in 2017 than in 2015 (14.7% (157/1061) vs. 19.2% (188/981); RR 0.77, 95% CI 0.64-0.94).
Achieving the UNAIDS target of 90% of HIV patients on treatment having VL suppression by 2020 is feasible in Oman.
评估阿曼国家艾滋病规划引入的能力建设干预措施对该国艾滋病毒护理质量的影响。
计算了干预措施引入前后（分别为 2015 年 12 月（n=1098）和 2017 年 6 月（n=1185））期间艾滋病毒病毒载量（VL）抑制和失访（LTFU）率：培训、支持和护理途径的发展。在感兴趣的年度的最后一次测量中，使用三个 HIV VL 截止值来定义 VL 抑制。
在意向治疗（ITT）分析中，VL<200 拷贝/ml 和 VL<1000 拷贝/ml 的比例从 2015 年的 51.9%增加到 2017 年的 65.5%（相对风险（RR）1.26，95%置信区间（CI）1.17-1.36）和从 2015 年的 58.1%增加到 2017 年的 70.9%（RR 1.22，95% CI 1.14-1.30）；两者均<0.0001。同样，在治疗中分析中，VL<200 拷贝/ml 和 VL<1000 拷贝/ml 的比例从 2015 年的 64.2%增加到 2017 年的 76.9%（RR 1.20，95% CI 1.12-1.28）和从 2015 年的 71.9%增加到 2017 年的 83.2%（RR 1.16，95% CI 1.10-1.22）。2017 年失访的患者少于 2015 年（14.7%（157/1061）比 19.2%（188/981）；RR 0.77，95% CI 0.64-0.94）。
在阿曼实现到 2020 年达到联合国艾滋病规划署 90%接受治疗的艾滋病毒患者病毒载量抑制的目标是可行的。
