Hupfeld Line, Pommergaard Hans-Christian, Burcharth Jakob, Rosenberg Jacob
Department of Surgery, Herlev Hospital, University of Copenhagen, Herlev Ringvej 75, 2730, Herlev, Denmark.
Department of Surgical Gastroenterology, Rigshospitalet, University of Copenhagen, Herlev, Denmark.
Int J Colorectal Dis. 2018 Jul;33(7):879-886. doi: 10.1007/s00384-018-3078-7. Epub 2018 May 22.
Acute colonic diverticulitis is common in the Western world representing a growing burden on health care. We aimed to report the factual epidemiological and demographic characteristics in patients with acute diverticulitis in a large nationwide population.
We conducted a population-based cohort study from 2000 to 2012 on the complete Danish population, which included all patients with acute colonic diverticulitis. Data were composed through two national longitudinal registries. The study main outcomes were demographic development regarding hospital admission, age, gender, geographical residency, and seasonal information.
A total of 101,963 acute hospital contacts were identified from 2000 to 2012, of these 44,160 were due to acute diverticulitis. From 2000 to 2012, overall admission rates for complicated diverticulitis increased significantly with 42.7%. There was a small increase in hospital admissions due to acute diverticulitis, and uncomplicated diverticulitis accounted for 83-88% of all admissions. No significant development was seen in cases of uncomplicated diverticulitis. The majority of patients were older than 50 years (85%) and 60% were women. The male gender dominated in patients younger than 50 years (58%), whereas women dominated above 50 years (63%). Mean age and dominating age group decreased significantly from 2000 to 2012 for both genders. A significantly larger proportion of male patients had complicated diverticulitis than uncomplicated diverticulitis. Most admissions were seen during autumn.
We found that acute colonic diverticulitis has been progressing over the last decade with more severe cases of disease. Our findings underline the need for further research to identify the relevant risk factors and causal circumstances.
急性结肠憩室炎在西方世界很常见,给医疗保健带来日益沉重的负担。我们旨在报告全国范围内大量急性憩室炎患者的实际流行病学和人口统计学特征。
我们于2000年至2012年对丹麦全体人口进行了一项基于人群的队列研究,其中包括所有急性结肠憩室炎患者。数据通过两个国家纵向登记处收集。研究的主要结果是关于住院、年龄、性别、地理居住情况和季节信息的人口统计学变化。
2000年至2012年共确定了101,963次急性住院接触,其中44,160次是由于急性憩室炎。从2000年到2012年,复杂性憩室炎的总体住院率显著上升了42.7%。急性憩室炎导致的住院人数略有增加,非复杂性憩室炎占所有住院人数的83 - 88%。非复杂性憩室炎病例未见显著变化。大多数患者年龄超过50岁(85%),60%为女性。50岁以下患者中男性占主导(58%),而50岁以上女性占主导(63%)。2000年至2012年,男女的平均年龄和主要年龄组均显著下降。男性患者中复杂性憩室炎的比例明显高于非复杂性憩室炎。大多数住院发生在秋季。
我们发现急性结肠憩室炎在过去十年中病情有所进展,出现了更多严重病例。我们的研究结果强调需要进一步研究以确定相关危险因素和因果情况。