Pohnán R, Ryska M, Kalvach J, Hána L, Henlín T, Pejchal J
Rozhl Chir. 2018 Spring;97(5):234-238.
Although several techniques of laparoscopic left pancreatectomy have already been developed through experiments on animals and human patients, there is still insufficient information about their pathophysiological mechanisms, especially the impact on surgical stress.
In a group of 10 pigs, open left pancreatectomy was performed, and the other group of 10 pigs underwent laparoscopic left pancreatectomy. Postoperative stress was compared by determining serum levels of leukocytes, interleukin 1, 6 and CRP from peripheral venous blood collection. The blood was collected prior to incision, 1 and 2 hours after incision, 24 hours after the beginning of the procedure, and on the 7th postoperative day.
No statistically significant difference was found between open and laparoscopic left pancreatectomy in the measured values of leukocytes, IL-1 and 6 and CRP.Key words: laparoscopy - left pancreatectomy surgical stress response interleukin 1 interleukin 6.
尽管通过对动物和人类患者的实验已经开发出了几种腹腔镜下左胰腺切除术技术，但关于其病理生理机制的信息仍然不足，尤其是对外科手术应激的影响。
在一组10头猪中进行开放性左胰腺切除术，另一组10头猪接受腹腔镜下左胰腺切除术。通过测定外周静脉血中白细胞、白细胞介素1、6和CRP的血清水平来比较术后应激。在切口前、切口后1小时和2小时、手术开始后24小时以及术后第7天采集血液。
在白细胞、IL-1、6和CRP的测量值方面，开放性和腹腔镜下左胰腺切除术之间未发现统计学上的显著差异。
腹腔镜检查 - 左胰腺切除术 手术应激反应 白细胞介素1 白细胞介素6
