Maijer Amanda, Gessner April, Trumpatori Brian, Varhus Janet D
Banfield Pet Hospital, Edina, MN.
Wake Veterinary Urgent Care, Knightdale, NC.
Top Companion Anim Med. 2018 Mar;33(1):21-28. doi: 10.1053/j.tcam.2018.02.001. Epub 2018 Mar 13.
It is well documented that physiological electric fields provide the earliest signals necessary to initiate cell proliferation, migration, and ultimately reepithelialization of wounds. Additionally, electricity is known to exert an antimicrobial effect. An electric field-generating wound dressing designed to mimic physiological electric fields has not been described in the small animal clinic. This article retrospectively reviews the use of a microcell battery-impregnated bioelectric dressing (BED) in 5 small animal patients with complex wounds. For each patient, product application and wound healing progress was monitored and documented over several weeks. Despite the severity of the wounds and being at high risk for infection, all presenting wounds treated with BED achieved complete closure within 4 weeks without becoming infected or requiring grafting. These cases provide early evidence that the use of the BED is feasible in a small animal clinic and may support healing while providing topical, nonantibiotic activity against wound pathogens.
有充分的文献记载，生理电场提供启动细胞增殖、迁移以及最终实现伤口再上皮化所需的最早信号。此外，已知电具有抗菌作用。在小动物临床中，尚未有设计用于模拟生理电场的产生电场的伤口敷料的相关描述。本文回顾性分析了5例患有复杂伤口的小动物患者使用微电池浸渍生物电敷料（BED）的情况。对于每例患者，在数周内监测并记录了产品应用情况和伤口愈合进展。尽管伤口严重且感染风险高，但所有接受BED治疗的伤口在4周内均实现完全闭合，未发生感染或需要植皮。这些病例提供了早期证据，表明在小动物临床中使用BED是可行的，并且在为伤口病原体提供局部非抗生素活性的同时，可能有助于伤口愈合。
