Yu Kaijia, Liu Chang, Yu Tao, Wang Xueyuan, Xu Cuiping, Ni Duanyu, Li Yongjie
Beijing Institute of Functional Neurosurgery, Xuanwu Hospital of Capital Medical University, Beijing 100053, China.
Beijing Institute of Functional Neurosurgery, Xuanwu Hospital of Capital Medical University, Beijing 100053, China.
J Clin Neurosci. 2018 Aug;54:122-125. doi: 10.1016/j.jocn.2018.04.050. Epub 2018 May 21.
The authors present a case of an out-of- body experience (OBE) that occurred in a child with intractable epilepsy when stimulating the anterior insular cortex (AIC) by intracranial electrodes. After destroying several sites precisely located at the left AIC by radiofrequency thermocoagulation, the patient's seizures disappeared, and the OBE could not be reproduced when repeatedly stimulating these sites. To our knowledge, it has never been reported that an OBE occurred in the AIC. We analyze the mechanism of an OBE mostly appearing in temporo-parietal junction (TPJ) and propose two perspectives for a possible mechanism involving the AIC causing the OBE.
作者报告了一例在一名患有顽固性癫痫的儿童中，通过颅内电极刺激前岛叶皮质（AIC）时发生体外体验（OBE）的病例。在通过射频热凝精确破坏位于左侧AIC的几个位点后，患者的癫痫发作消失，并且在反复刺激这些位点时无法再现OBE。据我们所知，从未有过在AIC发生OBE的报道。我们分析了OBE大多出现在颞顶叶交界处（TPJ）的机制，并提出了两种关于AIC导致OBE的可能机制的观点。
