Das M, Srivastava B N, Rao C K, Thapar B R, Sharma G K
National Malaria Eradication Programme, Delhi, India.
Med Vet Entomol. 1987 Jul;1(3):289-95. doi: 10.1111/j.1365-2915.1987.tb00357.x.
A field trial of malaria vector control was conducted in Phulbani district, Orissa, during 1984 and 1985. Indoor-spraying of pirimiphos-methyl emulsion formulation was undertaken at an application rate of 2 g/m2 in two sections (population 14,692) of Nuagaon Primary Health Centre. Houses in two adjacent sections (population 21,450) were sprayed with DDT a water dispersible powder (wdp) formulation at 1 g/m2 for comparison purposes. Operational problems in this area come from the tendency of tribal people to re-plaster over wdp applications. Pre-spray malariological indices in the trial area were 38% slide positivity rate, 37% slide falciparum rate and 12.1% annual parasite incidence. Densities of Anopheles annularis Van der Wulp, An. culicifacies Giles, An. fluviatilis Theobald and other potential malaria vectors were reduced in the pirimiphos-methyl trial area 2-35-fold more than in the area sprayed with DDT. Malariological indices were reduced by 65-68% in the pirimiphos-methyl sprayed area compared with only 26-35% reduction in the DDT sprayed area. Spraymen and villagers experienced no adverse side-effects from residual house-spraying with pirimiphos-methyl emulsion and it is concluded that this organophosphate product has advantages for malaria vector control, especially in operationally difficult situations.
1984年至1985年期间，在奥里萨邦的普尔巴尼地区进行了疟疾媒介控制现场试验。在努阿贡初级卫生中心的两个区域（人口14,692），以2克/平方米的施用量进行了甲基嘧啶磷乳液制剂的室内喷洒。为作比较，在相邻的两个区域（人口21,450）的房屋中，以1克/平方米的用量喷洒了滴滴涕水分散性粉剂（wdp）制剂。该地区的操作问题源于部落居民在喷洒wdp制剂后重新涂抹墙壁的倾向。试验区域喷洒前的疟疾学指标为：血片阳性率38%，恶性疟原虫血片率37%，年寄生虫发病率12.1%。在甲基嘧啶磷试验区域，环纹按蚊、库氏按蚊、溪流按蚊和其他潜在疟疾媒介的密度比喷洒滴滴涕的区域降低了2至35倍。与喷洒滴滴涕的区域仅降低26%至35%相比，喷洒甲基嘧啶磷的区域疟疾学指标降低了65%至68%。喷洒人员和村民在使用甲基嘧啶磷乳液进行房屋残留喷洒时未出现不良副作用，得出的结论是，这种有机磷产品在疟疾媒介控制方面具有优势，特别是在操作困难的情况下。
