Kasinathan Gunasekaran, Sahu Sudhansu Sekhar, Nallan Krishnamoorthy, Tharmalingam Vijayakumar, Swaminathan Subramanian, Behera Kali Prasad, Pradhan Madan Mohan, Purusothaman Jambulingam
Indian Council of Medical Research-Vector Control Research Centre, Medical Complex, Indira Nagar, Puducherry, India.
National Vector Borne Disease Control Programme, Odisha, India.
Acta Trop. 2019 Jun;194:123-134. doi: 10.1016/j.actatropica.2019.03.028. Epub 2019 Mar 31.
While, dichlorodiphenyl-trichloroethane (DDT) water dispersible powder (WDP) 75% is considered as the high performance long lasting formulation for indoor residual spraying (IRS), no information is available regarding the comparative epidemiological effectiveness of the two DDT formulations when used for IRS in Indian conditions. The current study was undertaken to compare the effectiveness of IRS using DDT WDP 75% @ one g active ingredient (AI)/m with that using DDT WDP 50% @ one g AI/m in controlling Anopheles fluviatilis and An. culicifacies, the primary vectors of malaria in the selected endemic areas of Odisha State. Although, cone-bioassay mortality after 8 months of post spraying on DDT 75% sprayed surfaces as well as on sprayed but mud plastered surfaces was higher than DDT 50%, the six entomological parameters viz. resting density indoors and outdoors, trap density indoors, parous rate, human blood index and infection rate of An. fluviatilis and An. culicifacies did not show any statistically significant difference in reduction/ changes from pre- to post-spray period between the two DDT formulations.
虽然，75% 的二氯二苯三氯乙烷（DDT）水分散粒剂（WDP）被认为是用于室内滞留喷洒（IRS）的高性能长效制剂，但在印度条件下，当这两种 DDT 制剂用于 IRS 时，关于它们的比较流行病学有效性尚无可用信息。当前的研究旨在比较在奥里萨邦选定的疟疾流行地区，使用每平方米 1 克活性成分（AI）的 75% DDT WDP 进行 IRS 与使用每平方米 1 克 AI 的 50% DDT WDP 进行 IRS 在控制溪流按蚊和致倦库蚊方面的有效性，这两种蚊子是疟疾的主要传播媒介。尽管在喷洒 DDT 75% 的表面以及喷洒后又涂抹泥浆的表面上，喷洒 8 个月后的锥形生物测定死亡率高于 DDT 50%，但在室内外静息密度、室内诱捕密度、产蚊率、人血指数以及溪流按蚊和致倦库蚊的感染率这六个昆虫学参数方面，两种 DDT 制剂在喷洒前到喷洒后的减少/变化上均未显示出任何统计学上的显著差异。
