Brown M H, Badura L L, Nunez A A
Department of Psychology and Neuroscience, Michigan State University, East Lansing 48824-1117.
J Biol Rhythms. 1988 Spring;3(1):59-69. doi: 10.1177/074873048800300105.
Intrahypothalamic injections of the excitotoxin N-methyl-D,L-aspartic acid (NMA) that destroyed the parvocellular regions of the paraventricular nucleus (PVN) prevented gonadal regression in male hamsters (Mesocricetus auratus) kept in short days (LD 6:18). After 17 weeks in short days, these NMA-injected animals had large, functional gonads and displayed all components of male sexual behavior. These findings confirm that neurons of the PVN are part of the pathway that mediates photoperiodism in hamsters.
向下丘脑内注射兴奋性毒素N-甲基-D，L-天冬氨酸（NMA），该毒素破坏了室旁核（PVN）的小细胞区，可防止处于短日照（光照周期为6小时光照：18小时黑暗，即LD 6:18）环境中的雄性仓鼠（金黄仓鼠）性腺退化。在短日照环境中饲养17周后，这些注射了NMA的动物具有大的、功能正常的性腺，并表现出雄性性行为的所有组成部分。这些发现证实，PVN的神经元是介导仓鼠光周期现象的通路的一部分。
