Chemistry, University of Southampton, University Road, Highfield, Southampton, SO17 1BJ, UK.
Chem Soc Rev. 2018 Jul 17;47(14):5266-5311. doi: 10.1039/c8cs00097b.
Although chiral mechanically interlocked molecules (MIMs) have been synthesised and studied, enantiopure examples are relatively under-represented in the pantheon of reported catenanes and rotaxanes and the underlying chirality of the system is often even overlooked. This is changing with the advent of new applications of MIMs in catalysis, sensing and materials and the appearance of new methods to access unusual stereogenic units unique to the mechanical bond. Here we discuss the different stereogenic units that have been investigated in catenanes and rotaxanes, examples of their application, methods for assigning absolute stereochemistry and provide a perspective on future developments.
虽然手性机械互锁分子（MIMs）已经被合成和研究过，但在报道的索烃和轮烷中，对映体纯的例子相对较少，而且系统的内在手性往往甚至被忽视。随着 MIM 在催化、传感和材料中的新应用的出现，以及获得机械键独特的不寻常立体中心的新方法的出现，这种情况正在发生变化。在这里，我们讨论了在索烃和轮烷中研究过的不同立体中心单元，介绍了它们的应用实例，以及确定绝对立体化学的方法，并对未来的发展进行了展望。
