Schoket B, Zilahy Z, Molnar J, Vincze I
Department of Biochemistry, National Institute of Hygiene, Budapest, Hungary.
In Vivo. 1987 May-Jun;1(3):185-7.
The short-term effect of three substituted phenylurea herbicides has been investigated on antipyrine plasma half-life in rats. Isoproturon was ineffective, while chlortoluron and diuron decreased the half-life significantly. There was a close correlation between antipyrine half-lives and induction of hepatic cytochrome P-450 dependent benzo(a)pyrene monooxygenase, 7-ethoxycoumarin O-deethylase and 7-ethoxyresorufin O-deethylase.
