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[不同年龄组前庭诱发肌源性电位的正常参考值]

[The normative values of vestibular evoked myogenic potentialin different age-groups].

作者信息

Bi X, Zhou H F, Su J, Zhang J, Wang M X

机构信息

Department of Otolaryngology,Tianjin Medical University General Hospital,Tianjin,300052,China.

出版信息

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2016 Jul 5;30(13):1016-1020. doi: 10.13201/j.issn.1001-1781.2016.13.003.

DOI:10.13201/j.issn.1001-1781.2016.13.003
PMID:29798028
Abstract

To obtain the normative values of vestibular evoked myogenic potential(VEMP),i.e.the threshold,latency,latency-interval,amplitude of healthy population in Tianjin medical university General hospital.These values will help clinical diagnosis.Seventy-five healthy individuals (39 males and 36 females,age from 21 to 70 years)were enrolled in this study.They were divided into 3 groups according to age:group 1(21-30 years),group 2(>30-50 years),group 3(>50-70 years).oVEMP and cVEMP were performed and the normative values were obtained.SPSS 19.0 was used to analyze the data.The response rate was 77.3% and 85.3% of oVEMP and cVEMP respectively in all subjects.The values of oVEMP:in group 1 response rate was 100%,amplitude was(8.29±1.25)μV and threshold value was(83.65±4.10) dBnHL.In group 2 response rate was 85.4%,amplitude was(6.32±1.21)μV and threshold value was(89.24±4.18) dBnHL.In group 3 response rate was 46%,amplitude was(4.26±1.20) μV,threshold value was(95.13±4.21) dBnHL.The values of cVEMP: in group 1 response rate was 100%,amplitude was(108.87±19.10)μV and threshold value was(84.54±4.35) dBnHL.In group 2 response rate was 83.3%,amplitude was(84.10±20.02)μV and threshold value was (90.33±4.29)dBnHL.In group 3 response rate was 72.0%,amplitude was(64.18±19.22)μV and threshold value was (95.19±4.30)dBnHL.The statistical analysis show significant difference in oVEMP/cVEMP response rate,threshold and amplitude among different age-groups(<0.05).No significant difference was found in N1,P1 latency and latency-interval among different age-groups(>0.05).The normative values of VEMP of healthy population in Tianjin medical university General hospital were obtained in this research.These VEMP data were used for the diagnosis of related diseases.

摘要

为获取天津医科大学总医院健康人群的前庭诱发肌源性电位(VEMP)的规范值,即阈值、潜伏期、潜伏期间隔、波幅。这些值将有助于临床诊断。本研究纳入75名健康个体(39名男性和36名女性,年龄21至70岁)。根据年龄将他们分为3组:第1组(21 - 30岁),第2组(>30 - 50岁),第3组(>50 - 70岁)。进行了眼震电图(oVEMP)和颈肌前庭诱发肌源性电位(cVEMP)检测并获得规范值。使用SPSS 19.0分析数据。所有受试者中oVEMP和cVEMP的反应率分别为77.3%和85.3%。oVEMP的值:第1组反应率为100%,波幅为(8.29±1.25)μV,阈值为(83.65±4.10)dBnHL。第2组反应率为85.4%,波幅为(6.32±1.21)μV,阈值为(89.24±4.18)dBnHL。第3组反应率为46%,波幅为(4.26±1.20)μV,阈值为(95.13±4.21)dBnHL。cVEMP的值:第1组反应率为100%,波幅为(108.87±19.10)μV,阈值为(84.54±4.35)dBnHL。第2组反应率为83.3%,波幅为(84.10±20.02)μV,阈值为(90.33±4.29)dBnHL。第3组反应率为72.0%,波幅为(64.18±19.22)μV,阈值为(95.19±4.30)dBnHL。统计分析显示不同年龄组之间oVEMP/cVEMP反应率、阈值和波幅存在显著差异(<0.05)。不同年龄组之间N1、P1潜伏期和潜伏期间隔无显著差异(>0.05)。本研究获得了天津医科大学总医院健康人群VEMP的规范值。这些VEMP数据用于相关疾病的诊断。

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