Fu H, Zhang Z L, Tang Z N, Liu Q L
Department of Surgical Oncology, Cancer Hospital Affiliated to Ningxia Medical University, Yinchuan, 750001, China.
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2017 Jul 20;31(14):1089-1092. doi: 10.13201/j.issn.1001-1781.2017.14.009.
To investigate the application value of carbon nanoparticle lymph tracer in Ⅵ lymph node dissection for papillary thyroid cancer.One hundred and forty-eight patients with papillary thyroid cancer from October 2015 to May 2016 were enrolled into the retrospective analysis. Seventy-five cases with carbon nanoparticle injected in operation were divided into observation group, while the other seventy-three cases without lymph tracer were divided into control group. The number of neck Ⅵ lymph nodes and metastatic lymph nodes between the two groups were compared, as well as the incidence of parathyroid injury and postoperative hypocalcemia. There were no significant difference in age, gender, tumor size, pathology or type of operation between the two groups(>0.05). Parathyroid injury incidence in the observation group significantly lower than the control group (5.33% vs 5.33%, < 0.05). There was significant difference in the number of neck Ⅵ lymph node dissection between the two groups (observation group: 6.51±4.65, control group: 4.42±3.10, < 0.05).Carbon nanoparticle injected as a lymph tracer in thyroid surgery is helpful, the characteristics of the parathyroid gland negative imaging can effectively decrease the rate of parathyroid gland injury.
探讨碳纳米颗粒淋巴示踪剂在甲状腺乳头状癌Ⅵ区淋巴结清扫术中的应用价值。回顾性分析2015年10月至2016年5月收治的148例甲状腺乳头状癌患者。将术中注射碳纳米颗粒的75例患者分为观察组,未使用淋巴示踪剂的73例患者分为对照组。比较两组颈部Ⅵ区淋巴结及转移淋巴结数量,以及甲状旁腺损伤发生率和术后低钙血症发生率。两组患者年龄、性别、肿瘤大小、病理类型或手术方式比较,差异均无统计学意义(>0.05)。观察组甲状旁腺损伤发生率明显低于对照组(5.33%比15.07%,<0.05)。两组颈部Ⅵ区淋巴结清扫数量比较,差异有统计学意义(观察组:6.51±4.65,对照组:4.42±3.10,<0.05)。甲状腺手术中注射碳纳米颗粒作为淋巴示踪剂有助于甲状旁腺负性显影,可有效降低甲状旁腺损伤率。