脑肿瘤的靶向治疗：它们能实现吗？
Targeted Therapies for Brain Tumors: Will They Ever Deliver?
机构信息
Brain Tumor and Neuro-Oncology Center, Cleveland Clinic, Cleveland, Ohio.
出版信息
Clin Cancer Res. 2018 Aug 15;24(16):3790-3791. doi: 10.1158/1078-0432.CCR-18-0855. Epub 2018 May 24.
Abstract
The strategy of using biologically targeted therapeutics for cancer has yet to translate into effective treatment of gliomas. The neuro-oncology community is beginning to recognize that phase 0 studies should be performed to account for the impact of the blood-brain barrier on the ability of a therapeutic to reach its target(s). .
摘要
利用针对生物靶点的治疗药物治疗癌症的策略尚未转化为胶质母细胞瘤的有效治疗方法。神经肿瘤学界开始认识到，应该进行 0 期研究，以说明血脑屏障对治疗药物到达其靶标（s）的能力的影响。
Zotero 插件