Clemetson C A, de Carlo S J, Burney G A, Patel T J, Kozhiashvili N, Taylor R A
Int J Gynaecol Obstet. 1978;15(6):515-21. doi: 10.1002/j.1879-3479.1977.tb00745.x.
Studies were made of 36 different nuts, grains, fruits and vegetables commonly used as human foods; each of these was fed to a group of ovariectomized rats for 10 days as a sole diet. The estrogenic activities of the foods were estimated by comparing the uterine weights, uterine fluid volumes and the vaginal cornification indices of each group of rats with those of groups fed other foods. Almonds, cashew nuts, peanuts, oats, corn, wheat and apples all showed estrogenic activity. The original sample of almonds showed the greatest estrogenic activity (p less than 0.01) which was confirmed by repetition of the experiment (p less than 0.01), but subsequent studies of other samples of almonds showed no estrogenic activity. Possible reasons for the disparity of the results with different lots of almonds are discussed.
对36种常用作人类食物的不同坚果、谷物、水果和蔬菜进行了研究；将每一种作为唯一的食物喂给一组去卵巢大鼠，持续10天。通过比较每组大鼠的子宫重量、子宫液体积和阴道角化指数与喂食其他食物组的这些指标，来评估食物的雌激素活性。杏仁、腰果、花生、燕麦、玉米、小麦和苹果均表现出雌激素活性。最初的杏仁样本显示出最大的雌激素活性（p<0.01），该实验重复后得到证实（p<0.01），但随后对其他杏仁样本的研究未显示出雌激素活性。讨论了不同批次杏仁结果存在差异的可能原因。
