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The relationship between eosinophilic esophagitis and esophageal cancer.嗜酸性粒细胞性食管炎与食管癌之间的关系。
Dis Esophagus. 2017 Jul 1;30(7):1-5. doi: 10.1093/dote/dox050.
2
Lack of proton pump inhibitor trial prior to commencing therapy for eosinophilic esophagitis is common in the community.在社区中,开始嗜酸性粒细胞性食管炎治疗前未进行质子泵抑制剂试验的情况很常见。
Dis Esophagus. 2018 May 1;31(5). doi: 10.1093/dote/dox143.
3
Epidemiology and Natural History of Eosinophilic Esophagitis.嗜酸性食管炎的流行病学与自然史
Gastroenterology. 2018 Jan;154(2):319-332.e3. doi: 10.1053/j.gastro.2017.06.067. Epub 2017 Aug 1.
4
Long-Term Treatment of Eosinophilic Esophagitis With Swallowed Topical Corticosteroids: Development and Evaluation of a Therapeutic Concept.吞咽局部用皮质类固醇对嗜酸性食管炎的长期治疗:一种治疗理念的发展与评估
Am J Gastroenterol. 2017 Oct;112(10):1527-1535. doi: 10.1038/ajg.2017.202. Epub 2017 Jul 18.
5
Health-Related Quality of Life and Costs Associated With Eosinophilic Esophagitis: A Systematic Review.健康相关生活质量与嗜酸性食管炎相关成本:系统评价。
Clin Gastroenterol Hepatol. 2018 Apr;16(4):495-503.e8. doi: 10.1016/j.cgh.2017.06.036. Epub 2017 Jun 24.
6
Lack of Knowledge and Low Readiness for Health Care Transition in Eosinophilic Esophagitis and Eosinophilic Gastroenteritis.嗜酸性食管炎和嗜酸性胃肠炎患者对医疗保健过渡的知识缺乏及准备不足。
J Pediatr Gastroenterol Nutr. 2017 Jul;65(1):53-57. doi: 10.1097/MPG.0000000000001415.
7
PPI Trial for Eosinophilic Esophagitis: Chaos in the Community.质子泵抑制剂治疗嗜酸性粒细胞性食管炎:社区的乱象。
J Clin Gastroenterol. 2018 Aug;52(7):590-595. doi: 10.1097/MCG.0000000000000813.
8
Cost Utility Analysis of Topical Steroids Compared With Dietary Elimination for Treatment of Eosinophilic Esophagitis.外用类固醇与饮食排除法治疗嗜酸性食管炎的成本效用分析
Clin Gastroenterol Hepatol. 2017 Jun;15(6):841-849.e1. doi: 10.1016/j.cgh.2016.11.032. Epub 2016 Dec 7.
9
Causes and Outcomes of Esophageal Perforation in Eosinophilic Esophagitis.嗜酸性食管炎患者食管穿孔的病因及转归
J Clin Gastroenterol. 2017 Oct;51(9):805-813. doi: 10.1097/MCG.0000000000000718.
10
The Six-Food Elimination Diet for Eosinophilic Esophagitis Increases Grocery Shopping Cost and Complexity.嗜酸性食管炎的六食物排除饮食增加了食品杂货购物成本和复杂性。
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嗜酸性食管炎的诊断与人寿保险保费增加有关。

A diagnosis of eosinophilic esophagitis is associated with increased life insurance premiums.

作者信息

Leiman D A, Kochar B, Posner S, Fan C, Patel A, Shaheen O, Keller C Y, Koutlas N T, Eluri S, Dellon E S

机构信息

Division of Gastroenterology, Duke University, Durham, NC.

Duke Clinical Research Institute, Durham, NC.

出版信息

Dis Esophagus. 2018 Aug 1;31(8). doi: 10.1093/dote/doy008.

DOI:10.1093/dote/doy008
PMID:29800243
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6102799/
Abstract

Eosinophilic esophagitis (EoE) is a chronic disease that can be diagnosed at any age, but is not associated with malignancy and does not shorten lifespan. It remains unknown whether an EoE diagnosis affects insurability or insurance premium costs. We therefore aimed to determine whether a diagnosis of EoE affects the costs of life insurance. Our investigation was a secret shopper audit study whereby we contacted national insurance companies in the United States to evaluate the effect of a diagnosis of EoE on life insurance premiums. We constructed standardized case scenarios for males and females, including a 25-year-old and a 48-year-old without other comorbid conditions, who either had or did not have a diagnosis of EoE. Companies were asked for their best estimate for a $100,000 whole life insurance policy. Comparisons between median premiums were made using the Mann-Whitney U test. There were 20 national life insurance companies contacted and a total of 73 quotes were obtained. The median premium rate was similar for EoE and non-EoE cases at the younger age ($828 [IQR $576-1,020] vs. $756 [IQR $504-$804]; P = 0.10). However, the premium for the older case without EoE was 19% less expensive compared to a case with EoE ($1990 [IQR $1,248-2,350] vs. $2,375 [IQR $2,100-2568; P = 0.02]. This finding was not explained by sex or state of residence. Based on these findings, we conclude that life insurance premiums are significantly more expensive in the older patient case with EoE when compared to the same case without EoE. Patients with EoE and their providers should be aware of the additional cost associated with this diagnosis.

摘要

嗜酸性食管炎(EoE)是一种可在任何年龄被诊断出的慢性疾病,但它与恶性肿瘤无关,也不会缩短寿命。EoE诊断是否会影响保险可保性或保险费用仍不清楚。因此,我们旨在确定EoE诊断是否会影响人寿保险费用。我们的调查是一项秘密购物者审计研究,通过联系美国的全国性保险公司来评估EoE诊断对人寿保险保费的影响。我们为男性和女性构建了标准化的病例场景,包括一名25岁和一名48岁且无其他合并症的患者,他们分别被诊断或未被诊断为EoE。我们向保险公司询问了一份10万美元终身人寿保险保单的最佳报价。使用曼-惠特尼U检验对保费中位数进行比较。我们联系了20家全国性人寿保险公司,共获得73个报价。在较年轻的年龄组中,EoE病例和非EoE病例的保费中位数相似(828美元[四分位距576 - 1020美元]对756美元[四分位距504 - 804美元];P = 0.10)。然而,与EoE病例相比,年龄较大的非EoE病例的保费便宜19%(1990美元[四分位距1248 - 2350美元]对2375美元[四分位距2100 - 2568美元;P = 0.02])。这一发现无法用性别或居住州来解释。基于这些发现,我们得出结论,与无EoE的同年龄病例相比,年龄较大的EoE患者的人寿保险保费要贵得多。EoE患者及其医疗服务提供者应意识到这一诊断带来的额外费用。