Faculty of Aquatic and Fisheries Sciences, Kafrelsheikh University, El-Geish St., 33516 Kafrelsheikh City, Egypt.
Faculty of Aquatic and Fisheries Sciences, Kafrelsheikh University, El-Geish St., 33516 Kafrelsheikh City, Egypt.
Int J Biol Macromol. 2018 Oct 1;117:25-29. doi: 10.1016/j.ijbiomac.2018.05.150. Epub 2018 May 22.
Skin protection and control of its microbial pathogens are highly important demands; natural biological agents are the ideals for that. Collagen (Cg) was extracted and characterized from skin and scales of Nile tilapia fish (Oreochromis niloticus), chitosan (Cts) was extracted from shrimp shells and extract of oak (Quercus infectoria) galls (OGE) was prepared. The antimicrobial potentialities of extracted agents, Cts and OGE, were qualitatively proved against skin pathogens, Staphylococcus aureus and Candida albicans, including both antibiotic sensitive and resistant strains, neither Cg nor negative control exhibited antimicrobial actions toward examined strain. The entire agents were loaded onto cotton fabrics and evaluated for antimicrobial actions and durability. Loaded textiles with the combined extracts' composite were the most effectual followed by individual treatments with OGE and Cts, respectively. Treated textiles upheld most of their antimicrobial activity after 2 laundering cycles toward all microbial pathogens. This invention could be consequently applied for production of skin protectant and hygienic fabrics.
皮肤保护和控制其微生物病原体是非常重要的需求；天然生物制剂是理想的选择。从尼罗罗非鱼（Oreochromis niloticus）的皮肤和鳞片中提取并表征了胶原蛋白（Cg），从虾壳中提取了壳聚糖（Cts），并制备了栎瘿提取物（OGE）。提取的试剂 Cts 和 OGE 的抗菌潜力已通过定性试验得到证实，可对抗皮肤病原体金黄色葡萄球菌和白色念珠菌，包括抗生素敏感和耐药菌株，Cg 和阴性对照均未对检查菌株表现出抗菌作用。将所有试剂负载到棉织物上，并评估其抗菌作用和耐久性。负载有复合提取物的纺织品是最有效的，其次是单独使用 OGE 和 Cts 的处理。经过 2 次洗涤循环后，处理过的纺织品对所有微生物病原体仍保持大部分抗菌活性。本发明可用于生产皮肤保护剂和卫生织物。
