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一种用于预测个体身体组织皮肤温度感受器温度的新型局部热生物热模型。

A new local thermal bioheat model for predicting the temperature of skin thermoreceptors of individual body tissues.

作者信息

Khiavi Negin Moallemi, Maerefat Mehdi, Zolfaghari Seyed Alireza

机构信息

Department of Mechanical Engineering, Tarbiat Modares University, Tehran, Iran.

Department of Mechanical Engineering, University of Birjand, P.O.B. 97175-376, Birjand, Iran.

出版信息

J Therm Biol. 2018 May;74:290-302. doi: 10.1016/j.jtherbio.2018.04.006. Epub 2018 Apr 24.

Abstract

Under non-uniform environments, the human body thermal perception depends on the thermal responses of cutaneous thermoreceptors (TRs) in different body parts. However, skin TRs thermal response includes static and dynamic parts depending on TRs temperature and its change rate, respectively. Thus, it is necessary to evaluate the time-dependent temperatures of cutaneous TRs in different body parts. The Pennes equation is one of the most important bioheat equations for computing the temperature of biological bodies, but, it has been used for evaluating the mean temperature of the whole body, considering average properties for all body parts. In the present study, the Pennes equation was solved for 16 body parts by considering appropriate thermal/physiological properties for each segment. In addition, a controlling system was added to the Pennes equation by applying the thermoregulatory mechanisms of 65-node Tanabe (65MN) model. The time-dependent skin temperatures of the 16 body segments were obtained by solving the localized thermoregulatory bioheat equation. The validation of the present model was carried out using published experimental data and a good agreement was found.

摘要

在非均匀环境下,人体的热感知取决于不同身体部位皮肤温度感受器(TRs)的热响应。然而,皮肤TRs的热响应分别取决于TRs的温度及其变化率,包括静态和动态部分。因此,有必要评估不同身体部位皮肤TRs随时间变化的温度。彭尼斯方程是计算生物体温度最重要的生物热方程之一,但它一直用于评估整个身体的平均温度,考虑的是所有身体部位的平均特性。在本研究中,通过考虑每个身体部位适当的热/生理特性,对16个身体部位求解了彭尼斯方程。此外,通过应用65节点田边(65MN)模型的体温调节机制,在彭尼斯方程中添加了一个控制系统。通过求解局部体温调节生物热方程,得到了16个身体节段随时间变化的皮肤温度。利用已发表的实验数据对本模型进行了验证,结果吻合良好。

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