Department of Rehabilitation Medicine, Weill Cornell Medicine, 525 East 68th St, New York, NY 10065, United States; Department of Psychiatry, Weill Cornell Medicine, 525 East 68th St, New York, NY 10065, United States; NewYork-Presbyterian Hospital, Weill Cornell Medical Center, 525 East 68th St, New York, NY 10065, United States.
Department of Rehabilitation Medicine, Weill Cornell Medicine, 525 East 68th St, New York, NY 10065, United States; School of Health and Natural Sciences, Mercy College, 555 Broadway, Dobbs Ferry, NY 10522, United States; NewYork-Presbyterian Hospital, Weill Cornell Medical Center, 525 East 68th St, New York, NY 10065, United States.
J Neurol Sci. 2018 Jul 15;390:54-62. doi: 10.1016/j.jns.2018.04.012. Epub 2018 Apr 9.
Cognitive assessment is an important component of inpatient stroke rehabilitation. Few studies have empirically evaluated the clinical utility of specific neuropsychological measures in this setting. We investigated the psychometric properties and clinical utility of a 30-minute neuropsychological battery developed by the National Institute of Neurologic Disorders and Stroke (NINDS) and the Canadian Stroke Network (CSN). Clinical data were analyzed from 100 individuals with mild-moderate stroke severity on an acute inpatient rehabilitation unit who completed the NINDS-CSN battery at admission. The battery comprised the Symbol-Digit Modalities Test (SDMT), Trail Making Test, Controlled Oral Word Association Test, Animal Naming, and the Hopkins Verbal Learning Test-Revised. We evaluated the battery's distribution of scores, frequency of impaired performance, internal consistency, and ability to predict rehabilitation gain and independence in cognitively-based instrumental activities of daily living (IADL) at discharge. Results indicated that the NINDS-CSN battery was sensitive to cognitive impairment, demonstrated moderately strong internal consistency, and predicted discharge IADL. The SDMT demonstrated the strongest sensitivity to impairment and predictive validity. The NINDS-CSN battery is a clinically useful assessment battery in acute inpatient stroke rehabilitation. Complex attention and processing speed performance may be most informative in predicting amount of rehabilitation gain and IADL functioning at discharge.
认知评估是住院脑卒中康复的一个重要组成部分。很少有研究从实证角度评估特定神经心理学测量方法在这种情况下的临床效用。我们研究了由美国国立神经病学与卒中研究院(NINDS)和加拿大卒中网络(CSN)开发的 30 分钟神经心理学测试的心理测量特性和临床效用。对急性住院康复病房中 100 名轻中度脑卒中患者的临床数据进行了分析,这些患者在入院时完成了 NINDS-CSN 测试。该测试包含符号数字模态测试(SDMT)、连线测试、词语流畅性测试、动物命名测试和霍普金斯词语学习测试修订版。我们评估了该测试的分数分布、受损表现的频率、内部一致性以及对康复增益和认知性日常生活活动(IADL)独立性的预测能力。结果表明,NINDS-CSN 测试对认知障碍敏感,具有中等强度的内部一致性,并能预测出院时的 IADL。SDMT 对损伤的敏感性和预测有效性最强。NINDS-CSN 测试是急性住院脑卒中康复的一种有用的临床评估测试。复杂注意力和处理速度表现可能最有助于预测康复增益和出院时 IADL 功能的程度。