Department of Bioenvironmental Chemistry, Chonbuk National University, Jeonju, 54896, Republic of Korea.
Sci Rep. 2018 May 25;8(1):8129. doi: 10.1038/s41598-018-26536-9.
Toxicities and color deformation were evaluated of essential oils of Melissa officinalis cultivated in France, Ireland, and Serbia and their constituents, along with the control efficacy of spray formulations (0.25, 0.5, and 1%) containing M. officinalis oils cultivated in France and its main compound against Dermatophagoides farinae and D. pteronyssinus adults. In a contact + fumigant bioassay, M. officinalis oil (France) was more active against D. farinae and D. pteronyssinus, compared to M. officinalis oils (Ireland and Serbia). Interestingly, color alteration of D. farinae and D. pteronyssinus was exhibited, changing from colorless to golden brown through the treatment with M. officinalis oils. The acaricidal and color alteration principle of three M. officinalis oils was determined to be 3,7-dimethyl-2,6-octadienal. M. officinalis oil (France) and 3,7-dimethyl-2,6-octadienal were significantly more effective in closed containers than in open containers, indicating that their acaricidal route of action was largely a result of vapor action. Sprays (0.5 and 1%) containing 3,7-dimethyl-2,6-octadienal and 1% spray containing M. officinalis oil (France) resulted in 100% mortality and color alteration against D. farinae and D. pteronyssinus. These results indicated that M. officinalis oil and 3,7-dimethyl-2,6-octadienal could be developed as a suitable acaricidal and mite indicator ingredient for the control of dust mites.
在接触+熏烟生物测定中，与来自爱尔兰和塞尔维亚的柠檬香蜂草油相比，法国柠檬香蜂草油对粉尘螨和屋尘螨更具活性。有趣的是，处理过的粉尘螨和屋尘螨颜色发生了变化，从无色变为金棕色。三种柠檬香蜂草油的杀螨和变色原理被确定为 3,7-二甲基-2,6-辛二烯醛。法国柠檬香蜂草油和 3,7-二甲基-2,6-辛二烯醛在密闭容器中的效果明显优于开放容器，表明它们的杀螨作用途径主要是通过蒸汽作用。含有 3,7-二甲基-2,6-辛二烯醛的喷雾（0.5% 和 1%）和含有法国柠檬香蜂草油（1%）的喷雾对粉尘螨和屋尘螨均导致 100%的死亡率和颜色变化。这些结果表明，柠檬香蜂草油和 3,7-二甲基-2,6-辛二烯醛可作为一种合适的杀螨剂和螨指示剂成分，用于控制尘螨。
