碘海醇在啮齿动物中的急性毒性。
Acute toxicity of iopentol in rodents.
作者信息
Michelet A A, Salvesen S, Renaa T
机构信息
Department of Pharmacology and Toxicology, Nycomed As, Oslo, Norway.
出版信息
Acta Radiol Suppl. 1987;370:41-4.
PMID:2980310
Abstract
Testing of the intravenous toxicity (LD50) of iopentol in mice and rats showed results comparable to the toxicity of non-ionic monomeric contrast media already in clinical use. Toxicity data suggest that iopentol may be a useful compound for use as an intravascular radiographic contrast medium.
摘要
对碘海醇在小鼠和大鼠体内的静脉毒性（半数致死量）进行测试，结果显示其毒性与临床已使用的非离子单体造影剂相当。毒性数据表明，碘海醇可能是一种可用作血管内造影剂的有用化合物。
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