Landy H J, Hinson J
Department of Obstetrics and Gynecology, George Washington University Medical Center, Washington, DC 20037.
Reprod Toxicol. 1987;1(3):203-5. doi: 10.1016/s0890-6238(87)80034-5.
The medical problems associated with cocaine ingestion, most notably cardiovascular side effects, have become evident as its use has become epidemic in the United States. Its effects on pregnancy and the developing fetus are similarly being recognized as more women of childbearing age are abusing cocaine. A case of placental abruption at 33 weeks' gestation following cocaine use is reported. A review of the pharmacodynamics, medical complications, teratogenic potential and effects in pregnancy is included.
随着可卡因在美国的使用日益泛滥,与摄入可卡因相关的医学问题,尤其是心血管方面的副作用,已变得愈发明显。随着越来越多育龄妇女滥用可卡因,其对妊娠及发育中胎儿的影响也同样受到了关注。本文报告了一例在使用可卡因后妊娠33周时发生胎盘早剥的病例。文中还包括了对可卡因药效学、医学并发症、致畸潜力及对妊娠影响的综述。