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干燥综合征的诊断与治疗进展。

Advances in the diagnosis and treatment of Sjogren's syndrome.

机构信息

Institute of Clinical Pharmacology, Anhui Medical University, Hefei,, 230032, Anhui, China.

Key Laboratory of Anti-inflammatory and Immune Medicine, Ministry of Education, Hefei, 230032, Anhui, China.

出版信息

Clin Rheumatol. 2018 Jul;37(7):1743-1749. doi: 10.1007/s10067-018-4153-8. Epub 2018 May 26.

Abstract

Sjogren's syndrome (SS) is a systemic autoimmune disease that primarily affects the exocrine glands, resulting in dryness of the eyes and mouth due to lymphocytic infiltration of the salivary and lacrimal glands along with arthritis, kidney, liver, and lung involvement, chronic fatigue, musculoskeletal pain, vasculitis, and so on. Considerable advance has been made for the classification and treatment of primary SS in the past few years. This article reviews the recent classification criteria for primary SS and briefly discusses the conventional and novel therapies of the disease.

摘要

干燥综合征(SS)是一种系统性自身免疫性疾病,主要影响外分泌腺,导致唾液腺和泪腺淋巴细胞浸润,出现眼干和口干,同时伴有关节炎、肾脏、肝脏和肺部受累、慢性疲劳、肌肉骨骼疼痛、血管炎等。在过去的几年中,原发性 SS 的分类和治疗取得了相当大的进展。本文回顾了原发性 SS 的最新分类标准,并简要讨论了该疾病的常规和新型治疗方法。

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