Jean Raymond A, Chiu Alexander S, O'Neill Kathleen M, Lin Zhenqiu, Pei Kevin Y
Department of Surgery, Yale School of Medicine, New Haven, Connecticut; National Clinician Scholars Program, Department of Internal Medicine, New Haven, Connecticut.
Department of Surgery, Yale School of Medicine, New Haven, Connecticut.
J Surg Res. 2018 Jul;227:137-144. doi: 10.1016/j.jss.2018.02.029. Epub 2018 Mar 15.
Current guidelines for small bowel obstruction (SBO) recommend a limited trial of nonoperative management of no more than 3-5 d. For patients requiring surgery, it is uncertain if sociodemographic factors are associated with disparities in the duration of the trial of nonoperative therapy.
The Healthcare Cost and Utilization Project National Inpatient Sample from 2012 to 2014 was queried for discharges with a primary diagnosis of SBO. Primary outcomes of interest were the effects of sociodemographic factors, including race, insurance status, and income on the rate of receiving any operative management for SBO, and subsequently, among patients managed surgically, the risk of operative delay, defined as operative management ≥ 5 d after admission. We did this by using logistic hierarchical generalized linear models, accounting for hospital clustering and adjusted for sex, age, comorbidity, and hospital factors.
Of the 589,850 admissions for SBO between 2012 and 2014, 22.0% underwent operations. Overall, 26.2% were non-White, including 12.2% Black and 8.6% Hispanic patients, and the majority (56.0%) had Medicare insurance coverage. Income quartiles were evenly distributed across the overall study population. In adjusted logistic regression, operative delay was associated with increased odds of in-hospital mortality (odds ratio 1.30 95% confidence interval [1.10, 1.54]). Adjusted for patient and hospital factors, Black patients were significantly more likely to receive operations for SBO, whereas Medicaid and Medicare patients were significantly less likely. However, Black, Medicaid, and Medicare patients who were managed operatively were significantly more likely to have an operative delay of 5 or more d. There was no significant association between income and operative management in adjusted regression models.
Significant disparities in the operative management were based on race and insurance status. Further research is warranted to understand the causes of, and solutions to, these sociodemographic disparities in care.
目前小肠梗阻(SBO)指南建议对非手术治疗进行不超过3 - 5天的有限试验。对于需要手术的患者,社会人口统计学因素是否与非手术治疗试验持续时间的差异相关尚不确定。
查询2012年至2014年医疗成本和利用项目国家住院样本中主要诊断为SBO的出院病例。感兴趣的主要结局是社会人口统计学因素的影响,包括种族、保险状况和收入对SBO接受任何手术治疗率的影响,随后,在接受手术治疗的患者中,手术延迟的风险,定义为入院后≥5天进行手术治疗。我们通过使用逻辑分层广义线性模型来进行分析,考虑医院聚类情况,并对性别、年龄、合并症和医院因素进行调整。
在2012年至2014年期间的589,850例SBO入院病例中,22.0%接受了手术。总体而言,26.2%为非白人,包括12.2%的黑人患者和8.6%的西班牙裔患者,大多数(56.0%)有医疗保险覆盖。收入四分位数在整个研究人群中分布均匀。在调整后的逻辑回归中,手术延迟与住院死亡率增加的几率相关(比值比1.30,95%置信区间[1.10, 1.54])。在对患者和医院因素进行调整后,黑人患者接受SBO手术的可能性显著更高,而医疗补助和医疗保险患者的可能性显著更低。然而,接受手术治疗的黑人、医疗补助和医疗保险患者手术延迟5天或更长时间的可能性显著更高。在调整后的回归模型中,收入与手术治疗之间没有显著关联。
手术治疗方面存在基于种族和保险状况的显著差异。有必要进行进一步研究以了解这些社会人口统计学护理差异的原因及解决方案。