Suad Kh A, Al-Shamire J S H, Dhyaa A A
Department of Animal Production, College of Agriculture, University of Baghdad, Baghdad, Iraq.
Department of Anatomy, Histology and Embryology, College of Veterinary Medicine, University of Baghdad, Baghdad, Iraq.
Iran J Vet Res. 2018 Winter;19(1):27-34.
Two hundred and sixteen day-old Ross-308 broiler chicks were allocated into 4 groups to study the impacts of different concentrations (0.0, 0.1, 0.15 and 0.2%) of β-hydroxy-methyl butyrate calcium (β-HMB-Ca), on values of tri-iodothyronin (T3) and tetra-iodothyronin (T4) hormones, liver enzymes [aspartate aminotransferase (AST) and alanine aminotransferase (ALT)], uric acid, peroxide, malondialdihyde (MDA), fatty acids and some histological parameters of small intestine (thickness of mucosa, height of villi, thickness of villi, depth of epithelial crypts and epithelial height). The biochemical results did not show any significant effect on T3 and T4 hormones and ALT while there was significant (P<0.01) decrease of AST in groups 2 and 3 and significant (P<0.05) decrease in uric acid in groups 2, 3 and 4 in comparison to control. In the liver, peroxide value (PV) and free fatty acids (FFA) were significantly (P<0.05 and P<0.01 respectively) decreased in groups 2 and 3 compared to control. The histological changes indicate significant values (P<0.05) in all parameters of duodenum in group 2 and 3, while those parameters of jejunum showed significant values (P<0.05) in most parameters of groups 2 and 4. In conclusion, the addition of β-HMB-Ca to the broiler diet from age 1 to 35 days has improved the levels of liver function enzymes and uric acid in the serum and lowered the parameters of oxidation in the liver with improved the maturity, performance and secretory activities of the small intestine in broiler chickens.
将216只1日龄的罗斯308肉鸡雏鸡分为4组，以研究不同浓度（0.0%、0.1%、0.15%和0.2%）的β-羟基-β-甲基丁酸钙（β-HMB-Ca）对三碘甲状腺原氨酸（T3）和四碘甲状腺原氨酸（T4）激素值、肝脏酶[天冬氨酸转氨酶（AST）和丙氨酸转氨酶（ALT）]、尿酸、过氧化物、丙二醛（MDA）、脂肪酸以及小肠一些组织学参数（黏膜厚度、绒毛高度、绒毛厚度、上皮隐窝深度和上皮高度）的影响。生化结果显示，对T3和T4激素以及ALT没有任何显著影响，而与对照组相比，第2组和第3组的AST显著降低（P<0.01），第2组、第3组和第4组的尿酸显著降低（P<0.05）。在肝脏中，与对照组相比，第2组和第3组的过氧化物值（PV）和游离脂肪酸（FFA）分别显著降低（P<0.05和P<0.01）。组织学变化表明，第2组和第3组十二指肠的所有参数有显著值（P<0.05），而空肠的这些参数在第2组和第4组的大多数参数中显示出显著值（P<0.05）。总之，在1至35日龄的肉鸡日粮中添加β-HMB-Ca可改善血清中肝功能酶和尿酸水平，降低肝脏中的氧化参数，并改善肉鸡小肠的成熟度、性能和分泌活动。
