Stravoravdi P, Polyzonis M, Demetriou T
Theagenion Cancer Institute, Symeonidis Research Center, Thessaloniki, Greece.
Histol Histopathol. 1987 Apr;2(2):213-6.
Bromocriptine and other dopaminergic agonists drugs are used in Parkinson's disease. In this paper we have studied the ultrastructure of striated muscle of mice after bromocriptine treatment. There was a tremendous increase in the number and size of mitochondria, as well as a very notable increase in the cristae. Some ultrastructure changes were also noted at the neuromuscular junctions. An explanation has been attempted in the light of other investigations concerning the relationship of microtubules and bromocriptine on the one hand, and microtubules and mitochondria on the other.
溴隐亭和其他多巴胺能激动剂药物用于治疗帕金森病。在本文中，我们研究了溴隐亭治疗后小鼠横纹肌的超微结构。线粒体的数量和大小大幅增加，嵴也显著增多。在神经肌肉接头处也观察到一些超微结构变化。根据其他关于微管与溴隐亭以及微管与线粒体关系的研究，我们尝试给出了解释。
