Baruah J K, Washington M, Kinder D
Department of Neurology, Medical College of Wisconsin, Milwaukee 53226.
Exp Pathol. 1988;33(4):207-12.
The ethanol induced skeletal muscle degeneration is multi-factorial. The morphological changes of the skeletal muscle are more pronounced in the mitochondria. The excessive concentration of calcium in the mitochondria, as shown by the electron-probe micro-analysis, within the first week of ethanol intoxication, even before the appearance of ultrastructural changes suggests that the calcium influx provokes the mitochondrial degeneration.
乙醇诱导的骨骼肌变性是多因素的。骨骼肌的形态学变化在线粒体中更为明显。电子探针微分析显示，在乙醇中毒的第一周内，甚至在超微结构变化出现之前，线粒体中钙的浓度过高，这表明钙内流引发了线粒体变性。
