淋巴结比率与外阴癌患者阳性淋巴结数量有关，具有预后价值。
Lymph node ratio has prognostic value related to the number of positive lymph nodes in patients with vulvar cancer.
机构信息
Department of Radiation Oncology, Xiamen Cancer Hospital, The First Affiliated Hospital of Xiamen University, Xiamen 361003, PR China.
Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou 510060, PR China.
出版信息
Future Oncol. 2018 Oct;14(23):2343-2351. doi: 10.2217/fon-2018-0279. Epub 2018 May 29.
AIM
We investigated the value of the number of positive lymph nodes (PLNs) and lymph node ratio (LNR) on survival of vulvar cancer patients.
METHODS
A total of 2332 patients with vulvar squamous cell carcinoma were included from the SEER program.
RESULTS
In multivariate analysis, the number of PLNs and LNR were independent prognostic indictors of survival outcomes, a higher number of PLNs and a higher LNR had poorer survival outcomes. An LNR >0.2 was associated with poor survival outcomes according to the number of PLNs.
CONCLUSION
The LNR has prognostic value related to the number of PLNs and may allow a more accurate determination of the lymph node status of vulvar cancer patients.
目的
本研究旨在探讨阳性淋巴结数目（PLNs）和淋巴结比率（LNR）对外阴癌患者生存的价值。
方法
本研究共纳入了来自 SEER 计划的 2332 例外阴鳞癌患者。
结果
多因素分析结果显示，PLNs 数目和 LNR 是生存结局的独立预后指标，PLNs 数目越多、LNR 越高，患者的生存结局越差。根据 PLNs 数目，LNR>0.2 与不良生存结局相关。
结论
LNR 与 PLNs 数目相关，具有预后价值，可能有助于更准确地确定外阴癌患者的淋巴结状态。
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