单细胞转录组谱分析原虫和后生动物寄生虫。
Single-Cell Transcriptome Profiling of Protozoan and Metazoan Parasites.
机构信息
Department of Microbiology & Immunology, Weill Cornell Medicine, New York, NY 10065, USA; Biochemistry, Cell & Molecular Biology Graduate Program, Weill Cornell Medicine, New York, NY 10065, USA; These authors made equal contributions.
Institute for Computational Biomedicine, Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY 10065, USA; Caryl and Israel Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY 10065, USA; Physiology, Biophysics and Systems Biology Graduate Program, Weill Cornell Medicine, New York, NY 10065, USA; These authors made equal contributions.
出版信息
Trends Parasitol. 2018 Sep;34(9):731-734. doi: 10.1016/j.pt.2018.04.009. Epub 2018 May 26.
Single-cell RNA sequencing (scRNAseq) technologies are changing the way we study populations of cells by allowing for an unbiased characterization of the composition of these populations. This Forum article highlights outstanding questions in parasitology that could benefit from scRNAseq and provides guiding thoughts for planning such experiments.
单细胞 RNA 测序 (scRNAseq) 技术正在改变我们研究细胞群体的方式，因为它可以对这些群体的组成进行无偏倚的描述。这篇论坛文章强调了寄生虫学中可以受益于 scRNAseq 的突出问题，并为规划此类实验提供了指导思路。
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