Sampath Nishanth, Singh Akanksha, Gopalakrishnan Shridhar, Thukral Anu, Sankar M Jeeva, Agarwal Ramesh, Jaryal Ashok Kumar, Deorari Ashok, Paul Vinod K
Indian J Physiol Pharmacol. 2016 Apr;60(2):200-204.
Study background: Measurement of delivered pharyngeal pressure during continuous positive airway pressure (CPAP) therapy is not in routine practice due to lack of a simple and affordable technique of intrapharyngeal pressure measurement. To overcome the lack of the gold standard solid-state catheter-tip pressure measurement technology in our set up, we improvised a novel method of pressure measurement and tested its validity in a simulated pharynx.
A low-cost pressure transducer was improvised by attaching an orogastric tube to its one end. The other end of the orogastric tube was sealed into an artificial pharynx - a 20 ml syringe. The pressure transducer readings were compared with that obtained by a digital manometer attached to the tip of the syringe. Bland-Altman statistic was used to quantify the measurement reliability of the novel method against the digital manometer. Effect of tube length on the measurement agreement was also studied. The developed technique was applied in new-borns.
RESULTS & CONCLUSION: Pressures measured by this technique were in good agreement with that obtained using a digital manometer. This technique has the potential to be used as an alternative to catheter-tip pressure transducers for bedside pharyngeal pressure measurement in new-born babies, especially in under-resourced setups.
研究背景：由于缺乏简单且经济实惠的咽内压测量技术，持续气道正压通气（CPAP）治疗期间输送的咽部压力测量并非常规操作。为了克服我们设备中缺乏金标准的固态导管尖端压力测量技术的问题，我们改进了一种新型压力测量方法，并在模拟咽部测试了其有效性。
通过将一根胃管连接到低成本压力传感器的一端来进行改进。胃管的另一端密封在一个人工咽部——一个20毫升的注射器中。将压力传感器的读数与连接到注射器尖端的数字压力计获得的读数进行比较。采用布兰德-奥特曼统计量来量化该新方法相对于数字压力计的测量可靠性。还研究了管长对测量一致性的影响。所开发的技术应用于新生儿。
该技术测量的压力与使用数字压力计获得的压力高度一致。该技术有潜力替代导管尖端压力传感器，用于新生儿床边咽部压力测量，尤其是在资源匮乏的环境中。
