伴有中性粒细胞减少的慢性T细胞淋巴细胞增多症。其与爱泼斯坦-巴尔病毒感染的关联。

Chronic T-cell lymphocytosis with neutropenia. Its association with Epstein-Barr virus infection.

作者信息

Herrod H G, Wang W C, Sullivan J L

出版信息

Am J Dis Child. 1985 Apr;139(4):405-7. doi: 10.1001/archpedi.1985.02140060087037.

DOI:10.1001/archpedi.1985.02140060087037

Abstract

Chronic T-cell lymphocytosis with neutropenia has primarily been reported in adults. We have cared for a 14-year-old patient with this condition for over five years. This patient consistently had greater than 90% lymphocytes in his differential cell count. The majority of these cells had the OKT8 phenotype. Serologic studies demonstrated evidence for a chronic Epstein-Barr infection with elevated antibody titers to both early antigen and to the viral capsid antigen. Patients presenting with this condition should be carefully evaluated for possible viral infection.

摘要

慢性T细胞淋巴细胞增多伴中性粒细胞减少主要在成人中报道。我们已经照料一名患有这种疾病的14岁患者超过五年。该患者的分类细胞计数中淋巴细胞始终超过90%。这些细胞中的大多数具有OKT8表型。血清学研究证明存在慢性EB病毒感染，早期抗原和病毒衣壳抗原的抗体滴度均升高。出现这种情况的患者应仔细评估是否可能存在病毒感染。