Ritchie J M
J Neurol Neurosurg Psychiatry. 1985 Mar;48(3):274-7. doi: 10.1136/jnnp.48.3.274.
Computer simulation of the action potential in myelinated nerve fibres show that the metabolic cost of conduction of an impulse is less than normal in a slightly depolarised fibre. This would account, at least in part, for the greater resistance to ischaemia and anoxia of nerves from diabetics and other pathophysiological conditions.
对有髓神经纤维动作电位的计算机模拟显示,在轻度去极化的纤维中,冲动传导的代谢成本低于正常情况。这至少可以部分解释糖尿病患者及其他病理生理状况下神经对缺血和缺氧的更大耐受性。