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A note on the mechanism of resistance to anoxia and ischaemia in pathophysiological mammalian myelinated nerve.关于病理生理状态下哺乳动物有髓神经对缺氧和缺血的抵抗机制的注释
J Neurol Neurosurg Psychiatry. 1985 Mar;48(3):274-7. doi: 10.1136/jnnp.48.3.274.
2
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[Sensory nerve action potentials in ischemia and compression in pressure paralysis and diabetes mellitus].
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8
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AN ION TRANSPORT DEFECT IN ERYTHROCYTES FROM UREMIC PATIENTS.尿毒症患者红细胞中的离子转运缺陷。
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THE ACTION POTENTIAL IN THE MYELINATED NERVE FIBER OF XENOPUS LAEVIS AS COMPUTED ON THE BASIS OF VOLTAGE CLAMP DATA.基于电压钳数据计算得出的非洲爪蟾有髓神经纤维动作电位
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Vibratory perception in diabetics during arrested blood flow to the limb.肢体血流阻断时糖尿病患者的振动觉
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Oxygen consumption of excised sympathetic ganglia at rest and in activity.离体交感神经节在静息和活动状态下的耗氧量。
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Oxygen consumption and phosphate efflux in mammalian non-myelinated nerve fibres.哺乳动物无髓神经纤维中的氧消耗和磷酸盐外流
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Potential clamp analysis of membrane currents in rat myelinated nerve fibres.大鼠有髓神经纤维膜电流的电压钳分析
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Changes in nodal function in nerve fibres of the spontaneously diabetic BB-Wistar rat: potential clamp analysis.自发性糖尿病BB-Wistar大鼠神经纤维中节点功能的变化:电压钳分析
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Effects of acute experimental diabetes on composite energy metabolism in peripheral nerve axons and Schwann cells.急性实验性糖尿病对周围神经轴突和施万细胞复合能量代谢的影响。
Diabetes. 1981 Nov;30(11):967-74. doi: 10.2337/diab.30.11.967.
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Neuropathy-functional abnormalities in the BB rat.BB大鼠的神经病变——功能异常
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Electron microscopic serial section analysis of nodes of Ranvier in lumbar spinal roots of the cat: a morphometric study of nodal compartments in fibres of different sizes.猫腰段脊神经根郎飞结的电子显微镜连续切片分析:不同大小纤维结间区的形态计量学研究
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关于病理生理状态下哺乳动物有髓神经对缺氧和缺血的抵抗机制的注释

A note on the mechanism of resistance to anoxia and ischaemia in pathophysiological mammalian myelinated nerve.

作者信息

Ritchie J M

出版信息

J Neurol Neurosurg Psychiatry. 1985 Mar;48(3):274-7. doi: 10.1136/jnnp.48.3.274.

DOI:10.1136/jnnp.48.3.274
PMID:2984336
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1028264/
Abstract

Computer simulation of the action potential in myelinated nerve fibres show that the metabolic cost of conduction of an impulse is less than normal in a slightly depolarised fibre. This would account, at least in part, for the greater resistance to ischaemia and anoxia of nerves from diabetics and other pathophysiological conditions.

摘要

对有髓神经纤维动作电位的计算机模拟显示,在轻度去极化的纤维中,冲动传导的代谢成本低于正常情况。这至少可以部分解释糖尿病患者及其他病理生理状况下神经对缺血和缺氧的更大耐受性。