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地上部分甲醇提取物的保肝作用评估

Evaluation of Hepatoprotective Effect of Eerial Part Methanolic Extract.

作者信息

Gazor Rouhollah, Asgari Mehrdad, Pasdaran Ardalan, Mohammadghasemi Fahimeh, Nasiri Ebrahim, Atrkar Roushan Zahra

机构信息

Cellular and Molecular Research Center, Guilan University of Medical Sciences, Rasht, Iran.

Student Research Center, Guilan University of Medical Sciences, Rasht, Iran.

出版信息

Iran J Pharm Res. 2017 Winter;16(Suppl):135-141.

Abstract

The aerial parts of was extracted by n-hexane, dichloromethane and methanol. Methanolic extract tested for hepatoprotective effects on formaldehyde liver injury in mice. The maximum effect that the methanolic extract showed protective effect on this experiment against formaldehyde observed in 5 and 10 mg. Also other concentrations of this extract showed positive effect compared to toxicant on morphology and biochemical factors of the liver. Results showed that the methanolic extract of the has a protective include functional and enzymatic stablingeffect on liver.

摘要

[植物名称]的地上部分用正己烷、二氯甲烷和甲醇进行提取。对甲醇提取物进行了对小鼠甲醛肝损伤的保肝作用测试。甲醇提取物在5毫克和10毫克时对该实验中甲醛所致肝损伤表现出最大的保护作用。此外,该提取物的其他浓度与毒物相比,对肝脏的形态和生化指标也显示出积极作用。结果表明,[植物名称]的甲醇提取物对肝脏具有包括功能和酶稳定作用在内的保护作用。

原文中“[植物名称]”处信息缺失。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3be/5963654/b94aac5e05fb/ijpr-16-135-g001.jpg

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